大学化学 >> 2017, Vol. 32 >> Issue (3): 1-14.doi: 10.3866/PKU.DXHX201612016

今日化学 上一篇    下一篇

应用电子圆二色光谱方法确定手性金属配合物的绝对构型

章慧*()   

  • 发布日期:2017-03-15
  • 通讯作者: 章慧 E-mail:huizhang@xmu.edu.cn
  • 基金资助:
    国家基础科学人才培养基金(J1310024);国家自然科学基金(21273175);国家自然科学基金(20973136);国家自然科学基金(20773098)

Application of Electronic Circular Dichroism Spectroscopic Methods in Determination of Absolute Configuration of Chiral Metal Complexes

Hui ZHANG*()   

  • Published:2017-03-15
  • Contact: Hui ZHANG E-mail:huizhang@xmu.edu.cn
  • Supported by:
    国家基础科学人才培养基金(J1310024);国家自然科学基金(21273175);国家自然科学基金(20973136);国家自然科学基金(20773098)

摘要:

与电子能级跃迁相关的电子圆二色(ECD)光谱因其研究对象宽泛,与涉及振动能级的振动圆二色(VCD)光谱互补,已成为应用于手性立体化学研究的集成手性光谱的主流表征手段。本文概述了确定手性金属配合物绝对构型的三种主要方法,详细介绍了ECD光谱法在确定手性金属配合物绝对构型中的应用,其中着重强调了激子手性方法,并对集成手性光谱学未来的发展趋势做出了展望。

关键词: 电子圆二色谱, 配位立体化学, 绝对构型关联, 激子手性方法, 集成手性光谱

Abstract:

Electronic circular dichroism (ECD) spectroscopy related to electron transition energy levels has become a mainstream characterization mean of the comprehensive chiroptical spectroscopy in the study on chiral stereochemistry, because of its wider research objects and mutual complementarity with vibrational circular dichroism (VCD) spectroscopy involving vibrational energy levels. In this paper, three main methods of determination of absolute configuration of chiral metal complexes are summarized. ECD spectroscopic methods are described in detail, among them exciton chirality method is emphasized. Additionally, this review points out the developing trend of the comprehensive chiroptical spectroscopy in the future.

Key words: Electronic circular dichroism, Coordination stereochemistry, Absolute configuration correlation, Exciton chirality method, Comprehensive chiroptical spectroscopy

MSC2000: 

  • G64