大学化学 >> 2021, Vol. 36 >> Issue (12): 2101026.doi: 10.3866/PKU.DXHX202101026

今日化学 上一篇    下一篇

芳香重氮盐参与的协同环加成反应

彭星, 张发光(), 马军安()   

  • 收稿日期:2021-01-13 录用日期:2021-03-03 发布日期:2021-03-29
  • 通讯作者: 张发光,马军安 E-mail:zhangfg1987@tju.edu.cn;majun_an68@tju.edu.cn
  • 作者简介:马军安, Email: majun_an68@tju.edu.cn
    张发光, Email: zhangfg1987@tju.edu.cn
  • 基金资助:
    国家自然科学基金(21772142);国家自然科学基金(21901181);国家自然科学基金(21961142015)

Aryl Diazonium Salts in Concerted Cycloaddition Reactions

Xing Peng, Fa-Guang Zhang(), Jun-An Ma()   

  • Received:2021-01-13 Accepted:2021-03-03 Published:2021-03-29
  • Contact: Fa-Guang Zhang,Jun-An Ma E-mail:zhangfg1987@tju.edu.cn;majun_an68@tju.edu.cn

摘要:

芳香重氮盐由于合成简单及多重反应性,在有机合成中占有重要地位。尽管芳香重氮盐的脱氮气交叉偶联反应、还原反应及与富电子芳烃的偶合反应已得到广泛应用,但是其参与的环加成反应却长期未受重视,在大学化学学习中也无相关介绍。值得注意的是,近年芳香重氮盐参与的成环反应日益增多,也为丰富和发展多样性的含氮杂环化合物提供了一种有效途径。因此,本文概述了芳香重氮盐协同环加成反应的最新进展及其在杂环合成方面的全新应用和机遇。

关键词: 芳香重氮盐, 环加成反应, 四氮唑, 三氮唑

Abstract:

Aryl diazonium salts are a class of important synthons in the field of organic synthesis due to their versatile reactivity and easy availability. Despite the widespread use of the denitrogenation-type cross-coupling, reduction, and azo-coupling reactions of aryl diazonium salts, the cycloaddition reactions of aryl diazonium salts have long been neglected. Noteworthy is that recent renaissance in this type of reactions has open powerful access to a diverse array of N-heterocycles. This minireview summarizes the latest development and applications of cycloaddition reactions of aryl diazonium salts as well as their new opportunity in organic synthesis.

Key words: Aryl diazonium salts, Cycloaddition, Tetrazoles, Triazoles

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