大学化学 >> 2022, Vol. 37 >> Issue (5): 2110074.doi: 10.3866/PKU.DXHX202110074

所属专题: 第2届全国大学生化学实验创新设计竞赛

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乙酸乙酯的可视化制备

鞠志宇(), 赵书珍, 孔灵钰, 杨莹莹   

  • 收稿日期:2021-10-25 录用日期:2022-01-06 发布日期:2022-03-08
  • 通讯作者: 鞠志宇 E-mail:juz1696l@163.com
  • 作者简介:鞠志宇, Email: juz1696l@163.com
  • 基金资助:
    河南省高等教育教学改革研究与实践项目(2019SJGLX404);河南省高等教育教学改革研究重点项目(2014SJGLX064)

Visualized Process for Preparing Ethyl Acetate

Zhiyu Ju(), Shuzhen Zhao, Lingyu Kong, Yingying Yang   

  • Received:2021-10-25 Accepted:2022-01-06 Published:2022-03-08
  • Contact: Zhiyu Ju E-mail:juz1696l@163.com

摘要:

在基础教学实验中引入可视化实验理念以强化酯化反应操作,对乙酸乙酯的制备实验进行了综合改进。以乙酸和乙醇为原料,硫酸氢钠为催化剂、变色硅胶为吸水剂、甲基紫为可视化试剂,实现了乙酸乙酯可视化制备,解决了试剂限购和碳化等问题。气相色谱分析结果表明乙酸几乎完全转化,并通过氢核磁共振(1H NMR)证实了乙酸乙酯产物结构。利用颜色明显变化进行化学反应过程可视化教学,让学生在视觉上感知酯化反应的动态过程,从而增强学生学习有机化学的兴趣,活跃学生的思维以及提高学生学习效率。

关键词: 乙酸乙酯, 可视化, 甲基紫, 制备

Abstract:

In order to introduce the concept of visualized experiment into basic laboratory teaching and to enhance the exercise on esterification, comprehensive improvement was made on the preparation of ethyl acetate. In this experiment, acetic acid reacts with ethanol to produce ethyl acetate in the presence of sodium bisulfate and allochroic silica gel, and the endpoint of the reaction is vidually indicated by methyl violet discoloration. This design of the reaction circumvents the problems of limited reagents and carbonization. The conversion was measured by gas chromatography, and the result showed that acetic acid was almost completely turned into the target product; the structure of the product was confirmed by 1H NMR. This experiment allows students to have a feel of the dynamic process of esterification by the discoloration of methyl violet with the increased acidity of the reaction system. Consequently, it can enhance students' interests in learning organic chemistry, enliven their thinking and improve their study efficiency.

Key words: Ethyl acetate, Visualization, Methyl violet, Synthesis

MSC2000: 

  • G64