大学化学 >> 2022, Vol. 37 >> Issue (12): 2111067.doi: 10.3866/PKU.DXHX202111067

化学实验 上一篇    下一篇

EDTA滴定法测药物制剂中的ZnO:定量分析在实践中的应用

赵宏伟, 槐佳孟, 王泽, 陈霞()   

  • 收稿日期:2021-11-24 录用日期:2021-12-27 发布日期:2022-02-10
  • 通讯作者: 陈霞 E-mail:chenxia@sxu.edu.cn
  • 作者简介:陈霞, Email: chenxia@sxu.edu.cn
  • 基金资助:
    山西省高等学校精品共享课程(K2020024);2021年山西省高等学校教学改革创新项目(J2021098);山西大学第十九期大学生创新创业训练项目(2021019345)

Complexometric Titration for the Determination of Zno in Pharmaceutical Preparations: Application of Quantitative Chemical Analysis in Practice

Hongwei Zhao, Jiameng Huai, Ze Wang, Xia Chen()   

  • Received:2021-11-24 Accepted:2021-12-27 Published:2022-02-10
  • Contact: Xia Chen E-mail:chenxia@sxu.edu.cn

摘要:

氧化锌可作为食品、化妆品和药品中的添加剂。本实验通过乙二胺四乙酸(EDTA)滴定法测定了痱子粉和皮肤软膏中ZnO的含量。以实际生活中的药品作为实验素材,发现配位滴定在质量控制中的实际应用,激发学生的学习兴趣,通过将实验结果与标签信息进行比较,更好地理解和掌握配位滴定法的原理、实验操作和定量分析实验结果的处理。

关键词: 配位滴定, 氧化锌, 分析化学实验

Abstract:

Zinc oxide is a usual additive in food, cosmetics, and pharmaceuticals. In this experiment, ZnO content in prickly heat powder and skin ointment was determined by complexometric titration using ethylenediaminetetraacetic acid (EDTA) as the titrant. With real-life pharmaceuticals as experimental materials, it could stimulate the students' interests in learning the applications of complexometric titrations in quality control. By comparing the experimental results with label information, the students could better understand and master the principle of complexometric titration, experimental operation and analysis of experimental results.

Key words: Complexometric titration, Zinc oxide, Analytical chemistry experiment

MSC2000: 

  • G64