University Chemistry ›› 2017, Vol. 32 ›› Issue (10): 39-46.doi: 10.3866/PKU.DXHX201704006

• Chemistry Laboratory • Previous Articles     Next Articles

A Comprehensive Innovation Experiment of Pharmaceutical Engineering on Extraction and Identification of Rutin, Preparation of Different Dosage Forms and Correlation with in Vivo Release

Hua-Nai LIU*(),Xiao-Yan LUO,Yong YE   

  • Published:2017-10-27
  • Contact: Hua-Nai LIU E-mail:liuhn@scut.edu.cn
  • Supported by:
    国家自然科学基金(81173646);华南理工大学教研教改重点项目(Y9160490)

Abstract:

The undergraduate innovative experiment plan is an important part of the Quality Project in colleges and universities. In the light of problem-based learning, this paper presents a comprehensive innovation experiment, that is, extraction and identification of rutin, preparation of different dosage forms and the correlation with in vivo release. Through this experiment, students can experience complete scientific research essentials, including searching literature, explaining experimental principle, establishing research ideas and strategies, preparing and characterizing samples, processing data, analyzing results, writing and submitting the experiment report. The key knowledges of extraction and purification of natural products, preparation of capsules and tablets, chemical properties of the matter, in vivo medicine release and other relevant knowledges can be fully grasped. Practices show that this experiment can effectively enhance students' comprehensive experimental skills and foster their innovative spirit and scientific research ability.

Key words: Rutin, Extraction, Medicine dosage form, In vivo release, Comprehensive innovation experiment

MSC2000: 

  • G64