University Chemistry ›› 2017, Vol. 32 ›› Issue (11): 57-64.doi: 10.3866/PKU.DXHX201707003

• Chemistry Laboratory • Previous Articles     Next Articles

Synthesis and Characterization of a BODIPY Fluorescent Probe and Its Application in Detection of Cu2+ Ions:A Comprehensive Chemical Experiment for College Students

Tian HE,Zheng-Ye GU,Yu-Fei ZENG,Yu-Zong HU,Shou-Chun YIN*()   

  • Published:2017-11-17
  • Contact: Shou-Chun YIN E-mail:yinsc@hznu.edu.cn
  • Supported by:
    浙江省“十二五”省级实验教学示范中心重点建设项目(浙教办函(2015)173号);杭州师范大学高等教育课堂教学改革研究项目

Abstract:

A new comprehensive chemical experiment for college students is introduced, including the synthesis and characterization of a fluorescent probe based on BODIPY, as well as its application in detection of Cu2+ ions. This experiment is from the achievements of scientific research. It includes the synthesis of 3, 5-dichloro-8-(4-tolyl)BODIPY, the synthesis of a fluorescent probe based on BODIPY, and the detection of metal ions by UV-Vis spectrometer and Fluorescence spectrometer. Students' interest in fluorescent sensor based on BODIPY research can be stimulated and cultivated by this experiment. Furthermore, the experiment involves the knowledge of organic chemistry, instrumental analysis and applied spectroscopy, which can be used to improve students' experimental skills, comprehensive and innovative abilities. Thus, it is recommended to be included in the advanced comprehensive chemical experiment course.

Key words: 3, 5-dichloro-8-(4-tolyl)BODIPY, Fluorescent probe, UV-Vis spectroscopy, Fluorescence, Comprehensive chemical experiment

MSC2000: 

  • G64