University Chemistry ›› 2018, Vol. 33 ›› Issue (7): 69-72.doi: 10.3866/PKU.DXHX201803033

Special Issue: 化学科普

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The Duality of Hemolysin: Application of Hemolysin in Genetic Sequencing

Ruocen TIAN1,Di WU2,3,4,*()   

  1. 1 Sichuan University-Pittsburgh Institute, Sichuan University, Chengdu 610207, P. R. China
    2 College of Chemistry, Sichuan University, Chengdu 610064, P. R. China
    3 Innovation & Entrepreneurship Office, Sichuan University, Chengdu 610064, P. R. China
    4 Department of Academic Affair, Sichuan University, Chengdu 610064, P. R. China
  • Received:2018-03-15 Published:2018-07-17
  • Contact: Di WU E-mail:wood@scu.edu.cn
  • Supported by:
    四川大学双创专题研究项目(SCUCXCY1725)

Abstract:

This is a virtual scientific fiction story. It mainly tells the story of a fictional character, Professor K, who finds staphylococcus alpha hemolysin that can be used as a nanopore in coincidence. When Professor K was thinking about the method of gene sequencing, he was inspired by the dream of Staphylococcus aureus attacking red blood cells. Finally, he got the method of nanopore sequencing from the dream.

Key words: Staphylococcus aureus alpha hemolysin, Nanoholes, Gene sequencing

MSC2000: 

  • G64