University Chemistry ›› 2019, Vol. 34 ›› Issue (6): 46-52.doi: 10.3866/PKU.DXHX201810023

• Chemistry Laboratory • Previous Articles     Next Articles

Selection and Teaching of Synthetic Experiments with Air-Sensitive Substances in Comprehensive Chemical Experiment

Xiaoxia ZHAO,Yinjuan BAI,Jingjing LIU,Hecong CHENG,Gang XIE*()   

  • Received:2018-10-23 Published:2018-12-28
  • Contact: Gang XIE E-mail:xiegang@nwu.edu.cn
  • Supported by:
    陕西省高校“一流专业”建设项目;国家自然科学基金(21371141);国家自然科学基金(21727805);陕西省自然科学基金(14JS091);陕西省自然科学基金(15JS114)

Abstract:

"Synthesis and characterization of an aryl silylamine" was selected as the teaching content of "Schlenk line technique", which involves drying and assembly of glass instruments for special purposes, operation of air sensitive substances, reactions under inert gas protection, solvent concentration, extraction, distillation under reduced pressure, and molecular structure determination. In this article, the following experimental operations were discussed in detail, including the preparation of experimental devices, the transfer of solvents and reactants, a special method of transferring n-butyllithium, operations of Schlenk line, Schlenk flasks and water-free solvent flasks. The hydrogen spectra of nuclear magnetic resonance (NMR) of the aryl silylamine were analyzed. This experiment enables students to practice the experimental operations at the higher levels. This could have a good teaching effect, in broadening students' professional knowledge and improving their operating skills in comprehensive chemical experiment.

Key words: n-Butyllithium, Aryl silylamine, Schlenk line technique, Comprehensive chemical experiment

MSC2000: 

  • G64