University Chemistry ›› 2020, Vol. 35 ›› Issue (1): 98-104.doi: 10.3866/PKU.DXHX201904048

• Chemistry Laboratory • Previous Articles     Next Articles

Design of Separation Experiment of Three Components of Benzoic Acid, p-Methylaniline and Acetanilide

Lihui Jiang,Guohui Chen,Weihong Wang,Yingping Zou*(),Yiming Luo   

  • Received:2019-04-26 Accepted:2019-08-19 Published:2019-09-05
  • Contact: Yingping Zou E-mail:yingpingzou@csu.edu.cn
  • Supported by:
    国家自然科学基金(21506258);湖南省自然科学基金(2017JJ2325)

Abstract:

Separation and purification is the key step in organic synthesis, which is 90% of the total work. To train undergraduates' laboratory skill of separation and purification from the crude product or mixture and improve their understanding ability of using the theory of extraction, distillation, recrystallization, the "Separation of three organic component mixtures" is arranged by the organic chemistry teaching group at the College of Chemistry and Chemical Engineering, Central South University. Students include the five-year and eight-year medical clinic, pharmaceutical and applied chemistry. In this paper, the two teaching schemes of acid and alkali separation in this experiment are discussed in detail, and the laboratory teaching effects of the two schemes are compared.

Key words: Three components, Separation and purification, Organic laboratory teaching, 1H NMR characterization

MSC2000: 

  • G64