University Chemistry ›› 2020, Vol. 35 ›› Issue (12): 227-232.doi: 10.3866/PKU.DXHX201911053

• Chemistry Laboratory • Previous Articles     Next Articles

Innovative Experiment for Students Based on Nobel Prizes in Chemistry: Construction of Fluorescent DPP Derivative by Suzuki Reaction

Jiukai Xiong1, Meijuan Zhao1, Yanan Wang1, Gang Bian1,*(), Ruixue Rong2,*(), Kerang Wang1,*()   

  1. 1 Key Laboratory of Medicinal Chemistry and Molecular Diagnosis(Ministry of Education), College of Chemistry and Environmental Science, Hebei University, Baoding 071002, Hebei Province, P. R. China
    2 Department of Immunology, School of Basic Medical Science, Hebei University, Baoding 071000, Hebei Province, P. R. China
  • Received:2019-11-25 Accepted:2020-02-19 Published:2020-02-27
  • Contact: Gang Bian,Ruixue Rong,Kerang Wang E-mail:13513408758@126.com;rongruixue_1234@163.com;kerangwang@163.com

Abstract:

Fluorescent diketopyrrolopyrrole (DPP) derivative was synthesized by coupling reaction, nucleophilic substitution reaction and Suzuki reaction, which was fully characterized by NMR spectroscopy and HRMS. Furthermore, the DPP derivative showed high fluorescence quantum yields of 88.4% and 78.9% in solvent and solid states.

Key words: Nobel Prizes in chemistry, Suzuki coupling reaction, Diketopyrrolopyrrole, Fluorescence

MSC2000: 

  • G64