University Chemistry ›› 2020, Vol. 35 ›› Issue (7): 187-189.doi: 10.3866/PKU.DXHX201912070

Special Issue: 有机化学课程与实验教学

• Self Studies • Previous Articles     Next Articles

Comparison between Nucleophilicity and Basicity Using the Principle of "Structure Determines Properties"

Xingyu Chen1, Xinyu Li1, Zhiqian Wang1,2,*()   

  1. 1 College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, P. R. China
    2 Office of Academic Affairs, Beijing University of Chemical Technology, Beijing 100029, P. R. China
  • Received:2019-12-25 Accepted:2020-03-19 Published:2020-03-30
  • Contact: Zhiqian Wang E-mail:wangzhq@mail.buct.edu.cn

Abstract:

This paper provides a practical explanation of the comparison between nucleophilicity and basicity of nucleophiles. The similarities are explained based on the principle of "structure determines property", and the differences are explained by combining Hard-Soft-Acid-Base theory and the steric hindrance factor.

Key words: Nucleophile, Nucleophilicity, Basicity

MSC2000: 

  • G64