University Chemistry ›› 2021, Vol. 36 ›› Issue (6): 2008082.doi: 10.3866/PKU.DXHX202008082

• Survey of Chemistry • Previous Articles     Next Articles

Research Progress in[1, 2]-Phospha-Brook Rearrangement Reaction

Xiyuan Zhang1, Yuming Li1, Zhiwei Miao1,2,*()   

  1. 1 State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, China
    2 State Key Laboratory of Efficient Utilization of Low- and Medium-grade Phosphate Ore and Its Associated Resources, Guizhou 550016, China
  • Received:2020-08-31 Accepted:2020-10-09 Published:2020-11-23
  • Contact: Zhiwei Miao E-mail:miaozhiwei@nankai.edu.cn

Abstract:

[1, 2]-Phospha-Brook rearrangement is an important organic name reaction that is widely used in several research fields such as organic synthetic chemistry and medicinal chemistry. This article reviews the recent progress of the[1, 2]-Phospha-Brook rearrangement reaction, with regard to its use in the synthesis of α-phosphoryloxy esters and different ternary, five- and six-membered cyclic functional compounds. We also provide insights into the future development direction of the[1, 2]-Phospha-Brook rearrangement reaction.

Key words: [1, 2]-Phospha-Brook rearrangement reaction, Asymmetric synthesis, Research progress

MSC2000: 

  • G64