University Chemistry ›› 2022, Vol. 37 ›› Issue (6): 2108011.doi: 10.3866/PKU.DXHX202108011

• Chemistry Laboratory • Previous Articles     Next Articles

Synthesis of Highly Efficient Ionic Liquid Catalysts and Their Application in Multi-Component Tandem Reactions

Ruopu Li, Yize Xu, Zhenglin Wang, Dazhen Xu()   

  • Received:2021-08-05 Accepted:2021-10-08 Published:2021-11-30
  • Contact: Dazhen Xu


In order to meet the requirements of the new era of experimental teaching, we introduced "ionic liquids" and "multi-component reactions" into the undergraduate experimental teaching course. Two kinds of 4H-pyran derivatives were prepared via a multi-component tandem reaction catalyzed by an ionic liquid catalyst. The experiment showed the follows advantages: Mild reaction conditions, observable process changes, high stability, and good reproducibility. The catalytic system is inexpensive and can be easily recycled and reused five times without any significant loss in its catalytic activity. This experiment are expected to help students establish the concept of "green chemistry". In addition, this experiment can be divided into several parts, thereby making it suitable for undergraduate teaching.

Key words: Green chemistry, Ionic liquid, Multi-component reaction, 4H-pyran derivatives, One-pot reaction


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