University Chemistry ›› 2022, Vol. 37 ›› Issue (3): 2111006.doi: 10.3866/PKU.DXHX202111006

Special Issue: 生物无机与大健康

• Chemistry Today • Previous Articles     Next Articles

Fluorescence Detection of Biological Endogenous SO2

Yuxin Wen, Hui Chao()   

  • Received:2021-11-01 Accepted:2021-11-14 Published:2021-12-29
  • Contact: Hui Chao


Sulfur dioxide (SO2) is well-known as an air pollutant, but SO2 can also be generated endogenously in organisms and participate in the metabolic cycle as a signal molecule, which has much to do with our health. Low concentration SO2 can dilate blood vessels, inhibit inflammation, fight oxidation and regulate lipid metabolism, while high concentration SO2 can cause some respiratory diseases, nervous system disorders and even cancer. Thus, a more in-depth and comprehensive understanding of SO2 is essential to the maintenance of homeostasis and health of biological systems in vivo. In this paper, by clue of the SO2 in living organisms, circulation of novel signal molecules exemplified by SO2 in living organisms and the evolution of detection methods are described from three aspects: endogenous generation, physiological functions in living organisms and modern fluorescence detection methods.

Key words: Endogenous sulfur dioxide, Physiological effect, Fluorescence detection


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