Wilhelmy吊片法测定磷脂溶液的表面张力等温线

doi:10.3866/PKU.DXHX202201014

Abstract

Abstract:

The determination of surface tension isotherm of surfactants is an important experiment of college physical chemistry laboratory. With the wide application of surfactants and the development of scientific instruments, it is necessary to update the experimental system of classical surface tension isotherm measurements. Herein, the surface tension isotherm of distearoyl phosphatidylcholine (DSPC) and dipalmitoyl phosphatidylcholine (DPPC) were determined by interfacial tensiometer, and the important parameters such as surface excess and cross-sectional area of molecules were calculated. An extended experiment was also suggested so as to promote the students' comprehensive knowledge and cultivate the students' ability to analyze and solve problems.

Key words: Phospholipid, Surface tension isotherm, Laboratory teaching

MSC2000:

G642.0

Yuanfei Li, Xunfang Yang, Guiling Wang, Ying Guo, Xu Wang, Xinru Li, Yanxia Zhou, Ying Xie. Determination of Surface Tension Isotherm of Phospholipid Solution Using Wilhelmy Method[J].University Chemistry, 2023, 38(1): 155-160.

Figures/Tables 5

References 9

1	Bulbake, U.; Doppalapudi, S.; Kommineni, N.; Khan, W.Pharmaceutics2017,9(2),12.
2	Mizushima, Y.; Yanagawa, A.; Hoshi, K.J. Pharm. Pharmacol.1983,35(10),666.
3	Reddy, B. P. K.; Yadav, H. K. S.; Nagesha, D. K.; Raizaday, A.; Karim, A.J. Nanosci. Nanotechnol.2015,15(6),4009. doi: 10.1166/jnn.2015.9713
4	Tenchov, R.; Bird, R.; Curtze, A. E.; Zhou, Q.ACS Nano2021,15(11),16982. doi: 10.1021/acsnano.1c04996
5	义光, 杜丽娜, 陈昱, 凌沛学纳米技术在药物递送中的应用,北京:化学工业出版社,2015,167-168.
6	周亭, 杨世超, 张志庆, 张国栋, 王芳珠, 张予辉, 王芳, 王秀凤实验技术与管理,2018,35(1),53.
7	Kawanishi, T.; Seimiya, T.; Sasaki, T.J. Colloid Interface Sci.1970,32(4),622. doi: 10.1016/0021-9797(70)90154-2
8	李武宏, 汪继红, 陈纪岳, 林玉龙, 徐璐, 崔黎丽, 谢英物理化学实验指导双语教材,第2版北京:民卫生出版社,2011,107-110.
9	Chaban, V.Chem. Phys. Lett.2014,616,25.

样品	m_max/μg	Γ_m/(mol∙m⁻²)	A/m²
DSPC	8.38	3.75 × 10⁻⁶	4.43 × 10⁻¹⁹
DPPC	13.53	6.53 × 10⁻⁶	2.54 × 10⁻¹⁹

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Determination of Surface Tension Isotherm of Phospholipid Solution Using Wilhelmy Method

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