University Chemistry ›› 2016, Vol. 31 ›› Issue (7): 1-13.doi: 10.3866/PKU.DXHX201512007

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Advances in Gadolinium(Ⅲ) Chelates as MRI Contrast Agents

Er-Yue DUAN,Jian-Gong MA,Peng CHENG*()   

  • Published:2016-07-26
  • Contact: Peng CHENG
  • Supported by:


In this paper, the Gd(Ⅲ)-based contrast agents are reviewed from four aspects as followed:principles, conditions, research progresses and approaches for improving relaxivity. The research progresses in the fields of fluorescent and biological contrast agents are deeply introduced. Moreover, the activity of enzyme, pH and metal ions of biological contrast agents are discussed.

Key words: Gd(Ⅲ)-based contrast agents, Principles, Relaxivity, Biological activity, Fluorescent sensor


  • O614.33