University Chemistry ›› 2017, Vol. 32 ›› Issue (4): 1-10.doi: 10.3866/PKU.DXHX201702002

• Chemistry Today • Previous Articles     Next Articles

Epitranscriptomic Modification-N6-Methyladenosine (m6A) and Plant Development

Lian-Huan WEI,Gui-Fang JIA*()   

  • Published:2017-04-20
  • Contact: Gui-Fang JIA E-mail:guifangjia@pku.edu.cn
  • Supported by:
    国家重点研发计划“精准医学研究”重点专项(2016YFC0900300)

Abstract:

Epitranscriptomic modification-N6-methyladenosine (m6A) is the most prevalent internal modification in eukaryotic mRNA. m6A has been well studied in mammals and proved to be dynamic and reversible. In mammals, it is installed by the m6Amethyltransferase complex (writers) and can be reversed by demethylases (erasers); it can be recognized by m6A-binding proteins (readers) to regulate RNA processing, such as splicing, stability, translation efficiency, nuclear export and so on. However, the research of m6A in plants is less limited. Here we summarize the latest progresses of m6A, especially m6A study in plants, and further discuss the potential impacts of m6A on plant growth and development, and responses to external stimuli.

Key words: N6-Methyladenosine (m6A), Epitranscriptome, m6A Methyltransferase, m6A Demethylase, m6A Binding protein

MSC2000: 

  • G64