卤代烷反应中取代和消去竞争的教学设计

doi:10.3866/PKU.DXHX202004088

Abstract

Abstract:

In the substitution and elimination reactions of haloalkanes, the attacking reagents are all negatively charged entities or multi-electron groups, so the competition reaction between substitution and elimination of haloalkanes is the key and difficult part of the teaching content. This article introduces the organization and design of this part of teaching contents, so that students can better understand and grasp this part including the influence of reaction substrates, attacking reagents and reaction conditions on dominant reactions and products. The instructional design plays an important role in training students' ability of analysis, thinking and flexible application of knowledge.

Key words: Haloalkane, Substitution reaction, Elimination reaction, Competition reaction, Instructional design

MSC2000:

Yunxia Wang, Junlong Zhao, Xiaofeng Gou, Ling Zhou, Lanying Wang. Instructional Design on the Competition Reactions between Substitution and Elimination of Haloalkanes[J].University Chemistry, 2020, 35(7): 190-201.

Figures/Tables 4

References 28

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$\mathrm{R}-\mathrm{Br}+\mathrm{C}_{2} \mathrm{H}_{5} \mathrm{O}^{-} \stackrel{\mathrm{C}_{2} \mathrm{H}_{5} \mathrm{OH}}{\longrightarrow} \text {取代产物}+\text {消去产物}$
R―Br	取代产物比例/%	消去产物比例/%
$\begin{array}{l}\;\;\;\;{\rm{C}}{{\rm{H}}_3}{\rm{C}}{{\rm{H}}_2}{\rm{Br}}\\\;\;{\rm{C}}{{\rm{H}}_3}{\rm{C}}{{\rm{H}}_2}{\rm{C}}{{\rm{H}}_2}{\rm{Br}}\\{\rm{C}}{{\rm{H}}_3}{\left( {{\rm{C}}{{\rm{H}}_2}} \right)_2}{\rm{C}}{{\rm{H}}_2}{\rm{Br}}\\\;\;{\rm{C}}{{\rm{H}}_3}{\rm{CHC}}{{\rm{H}}_2}{\rm{Br}}\\\;\;\;\;\;\;\;\;\mathop {\rm{C}}\limits^\| {{\rm{H}}_3}\end{array}$	99 91 90 40	1 9 10 60

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Instructional Design on the Competition Reactions between Substitution and Elimination of Haloalkanes

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