University Chemistry ›› 2016, Vol. 31 ›› Issue (9): 56-61.doi: 10.3866/PKU.DXHX201602015

• Chemistry Laboratory • Previous Articles     Next Articles

Analysis and Evaluation of Purity of Ethyl Acetate in the Esterification Reaction of Ethanol and Acetic Acid

Hua-Rong ZHAO*(),Huang-Ju CAI,Min-Rui QIN,Li-Ming YU,Dong-Bei SHAO   

  • Published:2016-09-30
  • Contact: Hua-Rong ZHAO E-mail:zhr0103@zju.edu.cn
  • Supported by:
    国家基础科学人才培养基金(J1210042);2015年浙江大学探究性实验教学研究项目

Abstract:

The gas chromatography method using internal standard and area normalization calibration and the NMR method using internal standard calibration are adopted for the determination of product purity in the synthesis of ethyl acetate. The purity of ethyl acetate detected by the GC internal standard method was the lowest. In contrast, the purity detected by the NMR internal standard method was the highest. The NMR internal standard method has more advantages, for this method can be used to complete the quantitative analysis and structural identification simultaneously, without the need to measure the correction factor.

Key words: Portable nuclear magnetic resonance spectrometer, Gas chromatography, Purity, Internal standard method, Area normalization calibration

MSC2000: 

  • O6-3