University Chemistry ›› 2017, Vol. 32 ›› Issue (2): 89-97.doi: 10.3866/PKU.DXHX201605023

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Discussion on the Theoretical Models and Practical Applications of Cooperative Effects

Yan-Yu LIANG1,3,Zhi-Peng WANG1,2,*()   

  1. 1 Chemistry Department, Tsinghua University, Beijing 100084, P. R. China
    2 Department of Chemistry, Texas A & M University, Texas 77840, USA
    3 Computational Biology Department, Carnegie Mellon University, Pennsylvania 15213, USA
  • Published:2017-02-11
  • Contact: Zhi-Peng WANG


This manuscript introducing "Cooperative Effect" starts from the fundamental physical chemistry principles, followed by the analysis of the mathematical models and the potential applications in combination with case studies from biochemistry, bioinorganic chemistry, enzymology, and supermolecular chemistry. We hope that the review can provide some help for the current fundamental education and research on route.

Key words: Cooperative effect, "S"-Shaped curve, Hill's equation, Hemoglobin, Biotin


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