University Chemistry ›› 2017, Vol. 32 ›› Issue (12): 69-73.doi: 10.3866/PKU.DXHX201706027

• Chemistry Laboratory • Previous Articles     Next Articles

Experimental Design: Colorimetric Detection of Levofloxacin Based on Silver Nanoparticles

Yan-Fang ZHAO,Lu-Bin XU*()   

  • Published:2017-12-19
  • Contact: Lu-Bin XU E-mail:qnd_xlb@163.com
  • Supported by:
    山东省高等学校精品课程项目(2013BK203);山东省高等学校精品课程项目(2013BK204);青岛农业大学应用型人才培养特色名校建设工程项目(XWLSP2013010);青岛农业大学应用型人才培养特色名校建设工程项目(XJG2013079);青岛农业大学实验技术研究课题;国家自然科学基金(21505083)

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Abstract:

A sensitive method based on the sodium dodecyl sulfate-stabilized silver nanoparticles (SDS-AgNPs) for detection of levofloxacin was reported. Levofloxacin could rapidly induce the aggregation of SDS-AgNPs, thereby resulting in a yellow-to-red color change. The color change could be monitored by naked eye and UV-Vis spectrophotometry. The presented method is convenient, simple, cost-effective and suitable for comprehensive laboratory teaching to develop students' innovation and scientific research ability.

Key words: Levofloxacin, Silver nanoparticles, Sodium dodecyl sulfate (SDS), Instrumental analysis experiment

MSC2000: 

  • G64