University Chemistry ›› 2017, Vol. 32 ›› Issue (12): 69-73.doi: 10.3866/PKU.DXHX201706027

• Chemistry Laboratory • Previous Articles     Next Articles

Experimental Design: Colorimetric Detection of Levofloxacin Based on Silver Nanoparticles

Yan-Fang ZHAO,Lu-Bin XU*()   

  • Published:2017-12-19
  • Contact: Lu-Bin XU
  • Supported by:


A sensitive method based on the sodium dodecyl sulfate-stabilized silver nanoparticles (SDS-AgNPs) for detection of levofloxacin was reported. Levofloxacin could rapidly induce the aggregation of SDS-AgNPs, thereby resulting in a yellow-to-red color change. The color change could be monitored by naked eye and UV-Vis spectrophotometry. The presented method is convenient, simple, cost-effective and suitable for comprehensive laboratory teaching to develop students' innovation and scientific research ability.

Key words: Levofloxacin, Silver nanoparticles, Sodium dodecyl sulfate (SDS), Instrumental analysis experiment


  • G64