University Chemistry ›› 2020, Vol. 35 ›› Issue (4): 168-172.doi: 10.3866/PKU.DXHX201911037

Special Issue: 全国大学生化学实验创新设计竞赛

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Improvement of the Cyclohexanone Preparation Experiment

Siyu Zhang1, Tianhui Hao1, Zeyue Wang1, Yun Yao1, Jian Ling1, Jingfeng Zhao2,*()   

  1. 1 School of Chemical Science and Technology, Yunnan University, Kunming 650091, P. R. China
    2 Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming 650091, P. R. China
  • Received:2019-11-20 Accepted:2019-12-11 Published:2019-12-26
  • Contact: Jingfeng Zhao E-mail:jfzhao@ynu.edu.cn

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Abstract:

The cyclohexanone preparation is an important experiment in fundamental organic chemistry laboratory for college students. In this paper, NaClO-TEMPO-TBAB catalytic oxidation reaction was used to replace chromic acid oxidation reaction, avoiding concentrated sulfuric acid and chromium-containing waste. At the same time, the reaction conditions were optimized to achieve small scale and shorten operating time which can train and improve students' operation skills in the experiment.

Key words: Cyclohexanol, Cyclohexanone, Catalytic oxidation, Phase transfer catalysis

MSC2000: 

  • G64