University Chemistry ›› 2021, Vol. 36 ›› Issue (4): 2005044.doi: 10.3866/PKU.DXHX202005044

• Chemistry Laboratory • Previous Articles     Next Articles

Comprehensive Experiment on Preparation and Application of pH-Responsive Nanoparticles

Yang Liu(), Qi Liu   

  • Received:2020-05-15 Accepted:2020-07-04 Published:2020-08-03
  • Contact: Yang Liu


In order to provide students with a more in-depth and intuitive understanding of the development and application of polymer materials in the field of nanotechnology, a comprehensive experiment was designed to focus on the design and biomedical applications of a novel-structured pH-responsive nanoparticle. This comprehensive experiment includes the synthesis of a pH-responsive block co-polymer via ring-opening polymerization, preparation of pH-responsive nanoparticles, and characterization and analysis of the polymer and the nanoparticles. This experiment helps students to understand the design principle and the basic processes of the preparation and characterization of polymer nanomedicine. This experiment involves the application of polymer science in the field of nanomedicine, which helps students to cultivate the ability to analyze and solve scientific problems, and stimulates the interest in exploring the frontiers of scientific research.

Key words: Polymer chemistry, Nanomedicine, pH response, Polymer materials


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