University Chemistry ›› 2020, Vol. 35 ›› Issue (12): 2-8.doi: 10.3866/PKU.DXHX202008080

Special Issue: 科学抗疫中的化学

• Special Subject • Previous Articles     Next Articles

Structures and Interactions of SARS-CoV-2's Spike Protein and Its Receptor

Hailong Yang1,2, Yun Liu2, Bin Yang1,*()   

  1. 1 Department of Biomedical Engineering, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, P. R. China
    2 School of Pharmaceutical Sciences, Guangdong Medical University, Dongguan 523808, Guangdong Province, P. R. China
  • Received:2020-08-31 Accepted:2020-10-15 Published:2020-10-30
  • Contact: Bin Yang


Biochemistry is a branch subject of chemistry, which is the study of chemical structures and processes associated with living organisms. COVID-19 pandemic is a problem for human beings. From the perspective of biochemistry, this paper demonstrates the chemical structure and interactions of SARS-CoV-2's spike protein and its receptor (human angiotensin converting enzyme 2), and summarizes the related research progresses. The authors hope to provide insights for the development of COVID-19 vaccine.

Key words: SARS-CoV-2, Spike protein, Angiotensin converting enzyme 2


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