利用二维核磁解析复杂有机分子的结构

doi:10.3866/PKU.DXHX202106023

Abstract

Abstract:

Two-dimensional NMR (2D NMR) is an effective tool for analyzing complex organic molecules and accurate assignments of their NMR signals. Herein, we showed three applications of 2D NMR on the structural analysis of complex molecules. Compared with 1D NMR, 2D NMR is advantageous due to the fact that it resolves the overlapped NMR signals much better by presenting those important parameters (chemical shifts and coupling constants, etc.) in two dimensions. In addition, 2D NMR provides the information of mutual-interactions of various nuclei. Therefore, 2D NMR can definitely help students to analyze the complex organic molecules.

Key words: 2D NMR spectroscopy, Structural analysis of complex molecules, Coupling constant

MSC2000:

Keyin Ye, Xianggui Zhang, Yaofeng Yuan. Structural Analysis of Complex Organic Molecules by Two-Dimensional Nuclear Magnetic Resonance Spectroscopy[J].University Chemistry, 2021, 36(9): 2106023.

Figures/Tables 10

References 10

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质子	化学位移(δ)	碳	化学位移(δ)
CH₃(1)	0.92	C(1)	7.8
CH₂(2)	1.94	C(2)	42.1
		CO(3)	209.0
CH₂(4)	1.92	C(4)	35.4
CH₂(5)	1.47	C(5)	23.7
CH₂(6)	1.11	C(6)	31.7
CH₂(7)	1.19	C(7)	22.7
CH₃(8)	0.82	C(8)	14.0

1-碘丁烷	化学位移(δ)	正丁醇	化学位移(δ)
CH₂(1’)	2.70	CH₂(1)	3.40
CH₂(2’)	1.39	CH₂(2)	1.39
CH₂(3’)	1.09	CH₂(3)	1.28
CH₃(4’)	0.62	CH₃(4)	0.83
		-OH	1.94

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Structural Analysis of Complex Organic Molecules by Two-Dimensional Nuclear Magnetic Resonance Spectroscopy

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