University Chemistry ›› 2021, Vol. 36 ›› Issue (9): 2106023.doi: 10.3866/PKU.DXHX202106023

Special Issue: 分析化学课程与实验教学

• Between Teacher and Student • Previous Articles     Next Articles

Structural Analysis of Complex Organic Molecules by Two-Dimensional Nuclear Magnetic Resonance Spectroscopy

Keyin Ye(), Xianggui Zhang, Yaofeng Yuan   

  • Received:2021-06-09 Accepted:2021-07-28 Published:2021-08-17
  • Contact: Keyin Ye


Two-dimensional NMR (2D NMR) is an effective tool for analyzing complex organic molecules and accurate assignments of their NMR signals. Herein, we showed three applications of 2D NMR on the structural analysis of complex molecules. Compared with 1D NMR, 2D NMR is advantageous due to the fact that it resolves the overlapped NMR signals much better by presenting those important parameters (chemical shifts and coupling constants, etc.) in two dimensions. In addition, 2D NMR provides the information of mutual-interactions of various nuclei. Therefore, 2D NMR can definitely help students to analyze the complex organic molecules.

Key words: 2D NMR spectroscopy, Structural analysis of complex molecules, Coupling constant


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