Adding matrix modifier is a common and efficient method to eliminate chemical interferences in graphite furnace atomic absorption spectrometry (GFAAS). The students' understanding of the choice and mechanism of matrix modifier is only at the textbook level. In the light of this, the multiple teaching modes are adopted to make students' learning activities changed from passive to active. Through literature investigation, group discussion, induction and summary and subsequent student experiments, the matrix modifier for the determination of heavy metal ions in environmental water samples by GFAAS is discussed in depth.

Strengthening the construction of course ideology and politics is very important for college education. It is an inevitable trend and urgent need for the implementation of the fundamental task of establishing morality in college education. This article introduces the overall thinking and practical exploration of curriculum ideological and political development in analytical chemistry. According to the characteristics of analytical chemistry, we select appropriate knowledge points to connect to the relevant content of ideological and political courses during the teaching of analytical chemistry. Through constructing an ideological and political case database, digging out the ideological and political elements in the frontiers of science, and carrying out flexible and diverse full coverage ideological and political teaching, the professional knowledge is effectively integrated with ideological and political education. In such a way, the content of ideological and political education can naturally penetrate into classroom teaching, and further cultivate and deepen students' awareness of home country feelings, cultural self-confidence, scientific spirit, civic awareness, and sound personality.

"Determination of calcium content in dolomite" is one of the important experiments in college analytical chemistry laboratory. During the experiment, students found that the initial redox reaction rates are significantly different between the calibration experiment of potassium permanganate solution by sodium oxalate standard solution and the titration experiment of calcium oxalate formed from dolomite by the calibrated potassium permanganate solution. Based on these experimental phenomena and combined with chemistry theory mastered by students, some conjectures and explanations were put forward. After that, we guided students to design experiments to explore and verify them. Through these experiments, it can not only answer the students' doubts, but also train and improve their ability to analyze and solve problems, and thus stimulating students' interest in chemical experiment learning.

The English course of "Separation Technology in Pharmaceutical Analysis" is an elective course for undergraduates in the College of Chemistry, Nankai University. In the teaching process, the effective teaching O-AMAS model (Objectives, Activation, Multi-learning, Assessment, Summary) introduced by the effective teaching team of Nankai University is integrated into the teaching of the course. The teaching concept of "learning for application, for promoting learning, and learning and using benefit each other" is well practiced.

In this paper, an innovative experiment of instrumental analysis was recommended to detect reduced glutathione (GSH) by using commercial reagent o-phthalaldehyde. The experiment involves preparation of standard solutions, spectra analysis, and measurement of ¹H nuclear magnetic resonance (NMR) spectroscopy and high resolution mass spectrometry (HR-MS). The implementation of this experiment can help students consolidate the basics knowledge of analytical chemistry and organic chemistry, understand the frontier scientific research, cultivate the scientific research ability and research ideas, and stimulate their enthusiasm for scientific research.

For complex acid-base solution system, it is difficult to deal with the proton equilibrium condition and deduce its proton balance equation (PBE). In this paper, taking FeCl₃ aqueous solution as a model, we discuss the treatment for proton equilibrium condition, and deduce systematically the proton balance equations based on various equilibrium relations in acid-base solution. These derivation results of PBE have been verified by different methods.

From the perspective of cultivating innovative talents in the new era, this paper expounds the necessity of reforming the teaching method of basic analytical chemistry experiment. In view of the basic analytical chemistry experiment in college, this paper puts forward the concrete rectification scheme from pre-class preparation, classroom teaching, experimental guidance, after-class discussion and summary to the method of experimental examination at the end of the semester. Compared with the traditional experimental teaching method, the implementation of the new method effectively improves the students' initiative in learning, and cultivates the students' solid experimental skills and innovative ability.

Large-scale instrumental analysis experiment has a unique position and attributes. The experimental procedure is closer to the actual analysis work, cultivating students' comprehensive ability of instrumental analysis. However, traditional approach can not realize the experiment teaching of large-scale instrumental analysis. Although the virtual simulation technology has solved some problems, it also causes the deviation between the virtual platform and the actual instrument. Taking the transmission electron microscope experiment as an example, this paper discusses how to effectively connect the virtual simulation technology with the teaching of actual instrument, and cultivate the students' comprehensive ability through the combination of virtual and actual teaching mode.

Analytical chemistry is an important basic chemistry course with quantity as the core. In the process of undergraduate talent cultivation of analytical chemistry in Sun Yat-sen University, the "quantity" is taken as the core to carry out the practice of "science and education integration" through multiple scientific research training and curriculum teaching. It enables students to gain a panoramic view of analytical chemistry and cultivate their innovation and creativity.

According to the general principles of classification and definition of concepts the concepts in the course of chemical analysis addressing metrical data are sorted out, including the basic tasks of chemometrics, accuracy, precision and error. Discussions are carried out on the arrangement of contents, concept terminology and definition of some concepts in the currently popular textbooks, and relevant suggestions are put forward, in the hope of providing reference for refining the textbooks of《Chemical Analysis》and standardizing academic terminology.

An analytical chemistry textbook is an important carrier for undergraduates to study analytical chemistry, stimulate innovation enthusiasm, cultivate innovative thinking and enhance innovation ability. Therefore, compiling of analytical chemistry textbooks that meet these requirements has become an important issue for analytical chemistry educators to think deeply and work on. In view of this, this paper introduced the authors' thinking and practice in the process of compiling an analytical chemistry textbook and the characteristics of the textbook. The authors hope to offer a good starting point for the analytical chemistry teaching peers.

The Limit of Detection and Sensitivity of analytical methods are two basic parameters for evaluating analytical methods. The International Union of Pure and Applied Chemistry (IUPAC) clearly recommends their definitions. However, both of them are still somewhat confused in some textbooks and research papers of analytical chemistry. Here, the definitions of both Limit of Detection and Sensitivity are clearly presented and the influence factors on Limit of Detection and Sensitivity of modern analytical methods are discussed. Some strategies to improve the Limit of Detection and the Sensitivity are proposed.

Analytical chemistry teaching team in Northeastern University constantly improves and explores new educational and teaching patterns. In the teaching of analytical chemistry theory course, the online and offline mixed teaching and bilingual teaching were implemented, and the ideological and political elements were integrated with contents of analytical chemistry. Analytical chemistry laboratory teaching is carried out using the MOOC platform and virtual simulation teaching project. On the basis of enhancing students' professional knowledge and training ability, students are trained to establish a rigorous and practical scientific attitude, and their patriotic feeling is enhanced.

Analytical chemistry laboratory is one of the basic courses for many majors in the universities. Since it starts in junior years, how to integrate ideological and political education elements into analytical chemistry laboratory has a great influence on building up the correct outlook on the world, life, values for the students, and it also has significant impact on cooperation education using the professional course and ideological and political course in the same direction. Using the complexometric titration experiment as an example, this paper introduces the excavation of ideological and political elements in Applied Chemistry major of Central South University, and constructs corresponding teaching cases, reflecting the teaching objectives and ideological and political education objectives of the course design.

Two-dimensional NMR (2D NMR) is an effective tool for analyzing complex organic molecules and accurate assignments of their NMR signals. Herein, we showed three applications of 2D NMR on the structural analysis of complex molecules. Compared with 1D NMR, 2D NMR is advantageous due to the fact that it resolves the overlapped NMR signals much better by presenting those important parameters (chemical shifts and coupling constants, etc.) in two dimensions. In addition, 2D NMR provides the information of mutual-interactions of various nuclei. Therefore, 2D NMR can definitely help students to analyze the complex organic molecules.

In order to improve the teaching quality and subjective initiative of the students, we carried out the competitive discussion teaching in instrumental analysis course under the situation of large-scale class even with multi-class teaching. The initial results show that the proposed teaching model can improve the students' initiative in course learning. It is also beneficial to promoting the all-round abilities of the students.

An instrumental analysis experiment "Determination of borneol isomer in wild chrysanthemum by chiral capillary gas chromatography" is recommended. Determination and quantitative analysis of (+)-borneol and (-)-borneol in wild chrysanthemum were conducted using chiral capillary gas chromatographic column in this experiment. Experimental contents consisted of extraction of volatile oil of wild chrysanthemum, optimization of heating program, application of internal standard curve method, etc. From the perspective of analytical chemistry, this experiment focuses on the types and separation principle of chiral chromatographic columns, and it is suggested to be set up as an expanding instrumental analysis experiment.

For the cultivation of top innovative talents at Dalian University of Technology in recent years, this paper elaborates the reflections and detailed procedures taken in reform of analytical chemistry course by reorganization of course contents, realization of student-oriented and question-oriented instructional design for the students to experience active leaning through Do-in-Learning and Learn-by-Doing.

This paper presents a discussion on using the distribution diagram to derive the titration curve concerning monoprotic acid.

Under the concept of blended learning, how to optimize the teaching design of analytical chemistry course and improve the effectiveness of teaching has become a subject that needs to be solved urgently. According to the characteristics of blended teaching, we take efforts to integrate high-quality digital curriculum resources, reconstruct teaching content, adopt diversified assessment indicators, and gradually enhance the connotation of curriculum. By focusing on students as the main body, interactive learning-oriented, emphasizing the construction process of knowledge, the implementations can enhance students' independent learning ability and comprehensive literacy, and ultimately achieve the teaching purpose of cultivating innovative talents.

In order to improve the teaching quality of analytical chemistry course, we carried out a series of reforms in the teaching of this course. Abundant informationized teaching resources have developed as the important support for the achievement of blended learning, which includes MOOC, wisdom teaching courseware by rain classroom, item bank APP and virtual simulation experiments. A new teaching method, namely "progressive OPPOs" has innovatively proposed and a cross-disciplinary collaborative teaching coupling with blended teaching was used for teaching reform as a new education mode in analytical chemistry course.

The teaching quality of quantitative analytical chemistry laboratory course is not only related to students' understanding of analytical chemistry, but also has a profound impact on their basic laboratory skill training. In this paper, from the perspective of a teaching assistant who is both a student and a teacher, we focus on several factors that affect the teaching quality of quantitative analysis chemistry laboratory course, and try to find a plan to improve the teaching quality, so as to provide reference for quantitative analytical chemistry laboratory course teaching.

This paper focuses on the topic of course ideology and politics in analytical chemistry teaching, and the research status on this topic has been summarized. The practical exploration has been carried out on the establishment of the educational goal, teaching exploration and the teachers' accomplishment. The ideological and political goal of integrating knowledge and action is expected to be realized by the ways of precise lecture preparation, optimization of classroom interaction and construction of feedback channels.

Conservation law is widespread in nature. Analytical chemistry is often related to many conservation laws, such as material conservation, charge conservation, proton conservation, electron conservation, etc. In analytical chemistry, conservation laws can be used to derive many formulas and to solve some complex calculation problems. In long-term teaching practice, the writers find that conservation laws can help students to understand many formulas, simplify the complicated process, consider the problem on an overall perspective, and not to consider trivial details.

The teaching of the modern spectral analysis course focuses on the cultivation of the comprehensive quality and ability of postgraduate students, and constantly explores how to carry out the course construction and teaching reform to achieve the course objectives: (1) We keep pace with the times and constantly update the teaching contents to reflect the scientific and cutting-edge nature of the course. (2) We integrate the ideological and political elements into the course of the modern spectral analysis to help the guidance on moral values of the graduate students. (3) We constantly innovate our teaching methods and explore flipped class, project-based learning, using intelligent teaching tools to manage teaching progress and construct diversified assessment methods.

An experiment of instrumental analysis for determination of caffeine content in beverages by Ultra Performance Convergence Chromatography (UPC²) was designed. The caffeine in three beverages including coke, green tea and oolong tea was extracted and diluted by methanol. Then caffeine concentrations in beverages were measured by UPC². Through this experiment, students could not only consolidate several laboratory skills such as weighing, constant volume and liquid transfer, but also master the basic theory, operation and data processing of UPC². This experiment integrates the new chromatography into basic laboratory teaching, which can broaden students' scientific horizons. It is conductive to cultivating students' innovative spirit and practical ability.

Based on the summary of the characteristics and existing problems of the instrumental analysis laboratory, the advantage of implementing virtual simulation technology was expounds. In addition, the outstanding performance of the virtual simulation laboratory teaching in dealing with special situations such as "classes suspended but learning continues" was introduced. Through questionnaires and interactive feedback, the learning situation of the students was evaluated. After pointing out the limitations of virtual simulation experiments, the teaching mode of combining online virtual simulation with offline classroom experiments was proposed, to promote the improvement of the quality of instrumental analysis laboratory teaching.

There are many problems in the process of chemistry laboratory teaching. For example, students have no research experience and time to think and explore, teachers are busy with imparting knowledge and have no time to consider students' personal needs. Analytical chemistry experiment course aims at cultivating innovative talents, by taking ideological and political education as the engine, experimental projects as the driving force, online courses as the support, and teaching platform as the vehicle. The "five methods linkage" teaching design has been implemented and completed, that is, before class preparation, problem speculation, practical exploration, frontier leading, competition-teaching combination. The design effectively activated the students' innovative practice ability, self-learning consciousness, team cooperation consciousness and innovative spirit; it also effectively helped establish the sense of national identity, social responsibility and historical mission, and ensured realization of the goal.

Analytical chemistry (I) is one of the core courses in chemistry major. We have performed the practical exploration, in which the scientific research achievements are integrated into the teaching contents and the latter are used to activate the research inspiration, in order to improve the teaching quality, enhance the students' interest in learning, and realize the mutual promotion between teaching and scientific research. The actual results are satisfactory.

The electronic nose is a high-tech product developed to simulate the olfactory organs of animals. As the core component of the electronic nose, the gas sensor converts information such as composition and concentration into electrical signal by reacting with the gas to be measured. The sensors can realize the fast, sensitive and real-time detection of harmful gases in the environment. This article introduces the basic principles and application fields of semiconductor, electrochemical, and infrared gas sensors, focusing on the research progress of gas sensors in recent years, and prospects for their future development.

Two indices addressing buffer solution are differentiated, which are used to gauge punctual and durative buffer function, respectively. Buffer strength β and buffer capacity α are accordingly suggested for the names of the indices (their corresponding mathematic expressions are differential formula and integral formula, respectively). The feasibility of introducing differential formula into calculation of durative capacity in the textbooks is intensively discussed, and the applicable conditions of this practice are pointed out, which forms the basis of suggestions for improvement on some contents of the textbooks.

This paper recommended an experiment of determination of 2,4-dichlorophenol in 2,4-D technical material using UV-Vis spectrophotometric method. The concepts of pesticide quality analysis and pesticide related impurities, the principle and application of ultraviolet spectrophotometer, and various sample pretreatment experimental skills such as weighing, vortexing and liquid transferring were involved, so as to enable students to master the methodology and data processing of quantitative determination using ultraviolet spectrophotometry. This experiment can exercise students' comprehensive experimental skills, cultivate their preliminary scientific research thinking, and enhance their practical application ability.

Innovation of experimental teaching mode is an important way to solve the current predicament of experimental teaching for science and engineering in universities. The difficulties in the teaching of analytical chemistry experiments were summarized in this paper. A new experimental teaching method was established relying on the basic, design and researching experiments as teaching contents, the micro-video as online preview before class, the discussion-based course of flipped classroom in class, and the combination of software for processing experimental results. This diversified teaching mode can effectively improve students' initiative and creativity. In addition, taking the basic and researching experiments as the examples, the application of the diversified teaching mode was performed, which will provide research basis for the reform of science and engineering experiment teaching.

Aptamers are a class of oligonucleotide sequences which have been widely used in molecular medicine and other fields due to their excellent affinity and selectivity to targets. As an important frontier technology and application, the research of aptamers will have an important impact on the cultivation of high-quality talents. Introducing frontier technologies and applications about aptamers in teaching is of great help to meet the needs of the country and society, cultivate students' sense of social responsibility, and heighten their spirituality. Thus frontier technologies and applications about aptamers are necessary for analytical chemistry teaching reform. In this paper, how frontier technologies and applications about aptamers influence ideological education of analytical chemistry teaching are briefly discussed.

Analytical chemistry (the part of quantitative chemical analysis) is an important course in many universities. The traditional system of the course can be characterized by "calculation through memorization" and "simplification through approximation". A large number of formulae not only result in heavy burden of memorization, but also tear the uniformity of the theory of chemical equilibrium. In order to solve such problems, a new formula-free system is designed. The new system features low demand on memorization and high level of uniformity, and makes accurate calculations possible. The details of the new system are presented in five aspects including background, characteristics, resources, examination and practices.

An undergraduate comprehensive electrochemical experiment was designed and developed. Based on the reversible cyclic voltammograms, the experiment was accomplished with a carbon nanotube modified electrode prepared by droplet coating. Using a Randles-Sevcik equation, the effective area of the electrode could be well calculated. Finally, the electrocatalytic detection of vitamin C was realized. The experiment described above partly filled up the shortage of teaching resources in cyclic voltammetry electrochemical technology for undergraduates. Thus, it shows a possibility of popularization among undergraduates.

A teaching experiment for determining copper(Ⅱ) ions in copper-containing sewage by UV-Vis spectrophotometry is designed. The experiment is performed based on the Fenton reaction principle, where the presence of copper(Ⅱ) ions in the assay solution catalyzes the decomposition of hydrogen peroxide to produce hydroxyl radicals. The latter oxidizes the colorless 3, 3', 5, 5'-tetramethylbenzidine (TMB) in the solution to the yellow TMB²⁺, which can be used for quantitative analysis copper(Ⅱ) ions in copper-containing sewage by measuring the absorbance of TMB²⁺ at 452 nm. With easy operation, short measurement time, excellent stability, eco-friendliness, this experiment conforms to the basic requirements of undergraduate laboratory teaching.