University Chemistry ›› 2022, Vol. 37 ›› Issue (12): 2111067.doi: 10.3866/PKU.DXHX202111067

• Chemistry Laboratory • Previous Articles     Next Articles

Complexometric Titration for the Determination of Zno in Pharmaceutical Preparations: Application of Quantitative Chemical Analysis in Practice

Hongwei Zhao, Jiameng Huai, Ze Wang, Xia Chen()   

  • Received:2021-11-24 Accepted:2021-12-27 Published:2022-02-10
  • Contact: Xia Chen


Zinc oxide is a usual additive in food, cosmetics, and pharmaceuticals. In this experiment, ZnO content in prickly heat powder and skin ointment was determined by complexometric titration using ethylenediaminetetraacetic acid (EDTA) as the titrant. With real-life pharmaceuticals as experimental materials, it could stimulate the students' interests in learning the applications of complexometric titrations in quality control. By comparing the experimental results with label information, the students could better understand and master the principle of complexometric titration, experimental operation and analysis of experimental results.

Key words: Complexometric titration, Zinc oxide, Analytical chemistry experiment