磷酰胺酯前药策略及ProTide技术在抗病毒药物研发中的应用

孙孝斌, 苗志伟

Application of Phosphoramidate Prodrugs Strategies and ProTide Technology in Anti-Virus Drug Discovery

Xiaobin Sun, Zhiwei Miao

图10 多功能手性咪唑二聚体催化剂用于前药MK-3682合成的磷酰胺酯化