大学化学 >> 2024, Vol. 39 >> Issue (4): 343-350.doi: 10.3866/PKU.DXHX202310076

化学实验 上一篇    下一篇

可见光诱导大茴香醛的高效合成

李杰, 钱汇达, 潘德阳, 王雯婧, 朱大亮, 房忠雪   

  1. 盐城师范学院化学与环境工程学院, 江苏 盐城 224007
  • 收稿日期:2023-10-19 修回日期:2023-12-11 发布日期:2024-01-04
  • 通讯作者: 朱大亮, 房忠雪 E-mail:zhudl@yctu.edu.cn;fangzhongxue120@163.com
  • 基金资助:
    江苏省教育厅面上项目(22KJB150048)

Efficient Synthesis of Anethaldehyde Induced by Visible Light

Jie Li, Huida Qian, Deyang Pan, Wenjing Wang, Daliang Zhu, Zhongxue Fang   

  1. School of Chemistry and Environmental Engineering, Yancheng Teachers University, Yancheng 224007, Jiangsu Province, China
  • Received:2023-10-19 Revised:2023-12-11 Published:2024-01-04

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摘要： 4-甲氧基苯甲醛，俗名大茴香醛，广泛应用于药物合成和香水调配等领域。但是传统合成大茴香醛的工艺缺点，导致其合成途径很难适合本科实验教学。本实验在温和且无金属的条件下，通过可见光诱导4-甲氧基苯甲醇来制备大茴香醛，这不仅提供了醇氧化、醛制备的新方法，而且也向学生拓展了光化学和自由基化学等重要知识，为培养具有科研思维和创新能力的新工科人才提供支撑。

关键词: 可见光诱导, 醇氧化, 无金属, 大茴香醛

Abstract: Anisaldehyde, also known as p-anisaldehyde, is widely used in the synthesis of pharmaceuticals and perfume formulation. However, the drawbacks of traditional methods for synthesizing anisaldehyde make it challenging to adapt them for undergraduate laboratory teaching. This experiment presents a novel approach to preparing anisaldehyde by mild and metal-free conditions, utilizing visible light-induced oxidation of p-anisyl alcohol. This not only offers a new method for alcohol oxidation and aldehyde preparation but also expands students’ knowledge in the fields of photochemistry and radical chemistry, which provides a support for cultivating new engineering talents with scientific research thinking and innovation capacity.

Key words: Visible-light-induced, Oxidation of alcohol, Metal-free, Anisaldehyde