药物递送魔法师——分子印迹聚合物

doi:10.12461/PKU.DXHX202409129

大学化学 >> 2025, Vol. 40 >> Issue (8): 202-210.doi: 10.12461/PKU.DXHX202409129

所属专题：高分子与生命健康

药物递送魔法师——分子印迹聚合物

骆玉霞¹, 解笑瑜², 陈方方¹

1 西北大学化学与材料科学学院, 化学国家级实验示范中心, 西安 710127;
2 西安交通大学医学部药学院, 西安 710061

收稿日期:2024-09-29 录用日期:2024-12-19 发布日期:2025-07-19
通讯作者: 陈方方 E-mail:chenff@nwu.edu.cn
基金资助:
国家自然科学基金面上项目(82373832)

The Magician of Drug Delivery: Molecularly Imprinted Polymers

Yuxia Luo¹, Xiaoyu Xie², Fangfang Chen¹

1 National Chemistry Experimental Teaching Demonstration Center, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China;
2 School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China

Received:2024-09-29 Accepted:2024-12-19 Published:2025-07-19
Contact: Fangfang Chen E-mail:chenff@nwu.edu.cn

摘要/Abstract

摘要： 分子印迹聚合物(MIPs)具有特异识别性和高选择性的优点，已被证明是一种有前途的药物递送系统(DDS)候选材料。MIPs-DDS在药物递送中可提供靶向和受控的药物释放，减少副作用，显著改善治疗效果。本文采用生动、拟人化的语言，介绍了MIPs的基本概念，并深入探讨了其在药物靶向递送中的应用及医药健康领域的应用前景。

关键词: 分子印迹聚合物, 靶向递送, 医药健康

Abstract: Molecularly imprinted polymers (MIPs), renowned for their specific recognition capabilities and high selectivity, have emerged as promising candidates for drug delivery systems (DDS). MIPs-based DDS enables targeted and controlled drug release, effectively minimizing side effects while significantly enhancing therapeutic outcomes. This article presents the fundamental concepts of MIPs using vivid, anthropomorphic language, followed by an in-depth exploration of their applications in targeted drug delivery and their potential in the pharmaceutical and healthcare sectors.

Key words: Molecular imprinting polymer, Targeted drug delivery, Medicine and health

骆玉霞, 解笑瑜, 陈方方. 药物递送魔法师——分子印迹聚合物[J]. 大学化学, 2025, 40(8): 202-210.

Yuxia Luo, Xiaoyu Xie, Fangfang Chen. The Magician of Drug Delivery: Molecularly Imprinted Polymers[J]. University Chemistry, 2025, 40(8): 202-210.

链接本文: https://www.dxhx.pku.edu.cn/CN/10.12461/PKU.DXHX202409129

https://www.dxhx.pku.edu.cn/CN/Y2025/V40/I8/202

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药物递送魔法师——分子印迹聚合物

The Magician of Drug Delivery: Molecularly Imprinted Polymers

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