大学化学 >> 2025, Vol. 40 >> Issue (8): 169-180.doi: 10.12461/PKU.DXHX202409143

所属专题: 高分子与生命健康

知识介绍 上一篇    下一篇

生命健康中的有机硅高分子

卢佳双1, 许晓阳1, 何有清2, 武明月1, 时瑞鑫1, 于文芳1, 卢杭3, 刘继3, 朱庆增1   

  1. 1 山东大学化学与化工学院, 特种功能聚集体材料教育部重点实验室, 济南 250100;
    2 山东师范大学附属中学, 济南 250100;
    3 浙江新安化工集团股份有限公司, 杭州 311600
  • 收稿日期:2024-09-30 录用日期:2024-12-19 发布日期:2025-07-19
  • 通讯作者: 朱庆增 E-mail:qzzhu@sdu.edu.cn
  • 基金资助:
    新安集团基础研究项目(2024);山东省泰山产业领军人才项目(tscx202312086)

Organosilicon Polymers in Life and Health Applications

Jiashuang Lu1, Xiaoyang Xu1, Youqing He2, Mingyue Wu1, Ruixin Shi1, Wenfang Yu1, Hang Lu3, Ji Liu3, Qingzeng Zhu1   

  1. 1 Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China;
    2 High School Attached to Shandong Normal University, Jinan 250100, China;
    3 Zhejiang Xin'an Chemical Industrial Group Co., Ltd. Hangzhou 311600, China
  • Received:2024-09-30 Accepted:2024-12-19 Published:2025-07-19
  • Contact: Qingzeng Zhu E-mail:qzzhu@sdu.edu.cn

摘要: 聚有机硅氧烷是一类主链由重复的Si―O键构成的高分子聚合物,主链Si原子上连接有机基团,是一类用途最广泛的有机硅高分子。这种无机-有机分子结构赋予了聚有机硅氧烷稳定的物理化学性能和生理惰性,生物相容性良好,耐候耐老化性能优异,加工性能好,广泛应用于修复或替换人体器官、美容整形、组织工程、医疗器械和药物载体等人类生命健康和日常生活领域,本文介绍了聚有机硅氧烷高分子的结构和性能,并对聚有机硅氧烷在生命和医疗健康领域的应用进行了详细论述。

关键词: 聚有机硅氧烷, 硅橡胶, 美容健康, 组织工程, 医疗器械, 药物载体

Abstract: Polysiloxanes, among the most versatile organosilicon polymers, feature a backbone composed of repeating Si―O bonds with organic groups attached to the silicon atoms. This unique inorganic-organic hybrid structure imparts exceptional physicochemical stability, physiological inertness, outstanding biocompatibility, remarkable weather and aging resistance, as well as excellent processability to polysiloxane materials. These superior properties have enabled their widespread applications in life sciences and healthcare, including human organ repair/replacement, cosmetic surgery, tissue engineering, medical devices, and drug delivery systems. This review systematically examines the structure-property relationships of polysiloxanes and provides a comprehensive discussion of their applications in biomedical and healthcare fields.

Key words: Polysiloxane, Silicone rubber, Cosmetic surgery, Tissue engineering, Medical devices, Drug carrier