大学化学 >> 2025, Vol. 40 >> Issue (8): 152-157.doi: 10.12461/PKU.DXHX202410032

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乙烯型卤代烃的亲核取代反应

孙柏林, 陈洁, 周岭   

  1. 西北大学化学与材料科学学院, 西安 710127
  • 收稿日期:2024-10-09 录用日期:2025-01-06 发布日期:2025-07-19
  • 通讯作者: 周岭 E-mail:zhoul@nwu.edu.cn
  • 基金资助:
    2023 年本科人才培养建设项目(2023033)

Nucleophilic Substitution Reaction of Vinylic Halides

Bolin Sun, Jie Chen, Ling Zhou   

  1. College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China
  • Received:2024-10-09 Accepted:2025-01-06 Published:2025-07-19
  • Contact: Ling Zhou E-mail:zhoul@nwu.edu.cn

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摘要： 在基础有机化学教材中，乙烯型卤代烃的亲核取代反应通常被认为是难以发生的。然而，随着近年来研究的深入，化学家们发现多例乙烯型卤代烃的亲核取代反应，并将这类反应命名为烯基亲核取代(Nucleophilic vinylic substitution，SNV)反应。本文主要介绍已提出的SNV反应的可能机理，并展示几个典型的SNV反应实例。将这些前沿进展融入课堂教学，不仅有助于学生了解SNV反应，而且能够丰富现有的亲核取代反应知识体系。

关键词: 乙烯型卤代烃, SNV反应, 亲核取代, 反应机理

Abstract: In organic chemistry textbooks, nucleophilic substitution reactions of vinylic halides are generally considered being difficult to occur. However, recent research has revealed numerous instances of these reactions, leading chemists to classify them as nucleophilic vinylic substitution (SNV) reactions. This article primarily explores the proposed mechanisms of SNV reactions and presents several representative examples. Integrating these cutting-edge advances into classroom teaching not only helps students understand SNV reactions but also enriches the existing knowledge system of nucleophilic substitution reactions.

Key words: Vinylic halides, SNV reaction, Nucleophilic substitution, Reaction mechanism