大学化学 >> 2025, Vol. 40 >> Issue (2): 247-250.doi: 10.12461/PKU.DXHX202405149

所属专题： 化学科普(2025)

科普 上一篇    下一篇

肌肉内的分子奥秘

窦子霄1, 沈执中1, 陈建成2   

  1. 1 南京大学新生学院安邦书院, 南京 210023;
    2 南京大学化学化工学院, 南京 210023
  • 收稿日期:2024-05-22 录用日期:2024-06-27 发布日期:2025-02-22
  • 通讯作者: 陈建成 E-mail:kschan@nju.edu.cn
  • 基金资助:
    南京大学百位名师邀约项目；南京大学国际化课程建设项目；南京大学短期国外专家项目

Unveiling the Molecular Mysteries inside Muscles

Zixiao Dou1, Zhizhong Shen1, Kin Shing Chan2   

  1. 1 Anbang Academy, College of First-Year Students, Nanjing University, Nanjing 210023, China;
    2 School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
  • Received:2024-05-22 Accepted:2024-06-27 Published:2025-02-22
  • Contact: Kin Shing Chan E-mail:kschan@nju.edu.cn

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摘要： 讲述主人公小周与小黄在新冠疫情后重拾运动过程中所面临的种种挑战。小周在长时间不运动后，急于恢复身体状态，却因为过量运动而导致身心疲惫，甚至比之前的状态更差。文章据此引出肌浆网的生理功能，同时探讨了γ-氨基丁酸(GABA)、5-羟色胺(5-HT)等物质由于运动引起变化进而影响心情感受的化学过程，以及过量运动会引起皮质醇这一化学物质的增加，并说明它对肌肉增长的不利。最后，讨论了锻炼对肌肉纤维的影响。

关键词: 运动, 肌浆网, γ-氨基丁酸, 5-羟色胺, 皮质醇, 肌肉纤维

Abstract: This article narrates the challenges faced by protagonists Xiao Zhou and Xiao Huang as they resume exercise after the COVID-19 pandemic. Xiao Zhou, having been inactive for a prolonged period, seeks to regain physical fitness but overexerts himself, leading to physical and mental exhaustion and a decline in condition. The article explores the physiological role of the sarcoplasmic reticulum and delves into the chemical processes involving γ-aminobutyric acid (GABA), 5-hydroxytryptamine (5-HT), and cortisol, influenced by exercise and impacting mood and muscle growth adversely. Additionally, it examines the effects of exercise on muscle fibers.

Key words: Exercise, Sarcoplasmic reticulum, γ-Aminobutyric acid (GABA), 5-Hydroxytryptamine (5-HT), Cortisol, Muscle fiber