大学化学 >> 2026, Vol. 41 >> Issue (3): 336-342.doi: 10.12461/PKU.DXHX202503114

所属专题： 化学科普(2025)

科普 上一篇    下一篇

“最佳多面手”颁奖典礼——透明质酸家族的荣耀时刻

郭兴1, 朱荣秀2   

  1. 1 山东大学基础医学院, 济南 250102;
    2 山东大学化学与化工学院, 济南 250100
  • 收稿日期:2025-03-26 录用日期:2025-05-21 发布日期:2026-03-24
  • 通讯作者: 朱荣秀 E-mail:rxzhu@sdu.edu.cn RongXiu Zhu
  • 基金资助:
    山东省自然科学基金(ZR2023MB072)；山东大学教育教学改革研究项目(2023Y061, 2024Y123)

“Best All-Rounder” Award: Celebrating Hyaluronic Acid’s Multifaceted Applications

Xing Guo1, RongXiu Zhu2   

  1. 1 College of Basic Medical Sciences, Shandong University, Jinan 250102, China;
    2 School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
  • Received:2025-03-26 Accepted:2025-05-21 Published:2026-03-24
  • Contact: RongXiu Zhu E-mail:rxzhu@sdu.edu.cn

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摘要： 透明质酸，又称玻尿酸，是一种重要的生物大分子，最早由眼科教授Meyer及其团队从牛眼玻璃体中分离得到。作为一种非硫酸化糖胺聚糖，透明质酸凭借其独特的生物学功能和卓越的多领域应用，被誉为“最佳多面手”。从医药领域到化妆品，再到食品健康，它的贡献无处不在。在医学上，它广泛应用于关节保健、眼科手术和皮肤填充等方面；在化妆品行业，凭借出色的保湿功效，它被视为护肤界的“天后”；在食品领域，因其对健康和美丽的双重促进作用，它备受人们青睐。本文以一场“最佳多面手”颁奖典礼为线索，拟人化地展现透明质酸在多个领域的独特魅力与卓越贡献，并揭示其背后的化学奥秘，带领读者一同感受这一多功能生物大分子在现代生活中的精彩表现。

关键词: 透明质酸, 糖胺聚糖, 多功能生物大分子

Abstract: Hyaluronic acid (HA), also known as hyaluronan, is an important biological macromolecule that was first isolated from the bovine vitreous humor by Professor Meyer and his team. As a non-sulfated glycosaminoglycan, HA has earned its reputation as “best all-rounder” due to its unique biological functions and wide-ranging applications. Its contributions span medicine, cosmetics, and food industries. In medicine, it finds applications in joint care, ophthalmic surgery, and dermal fillers. In the cosmetics industry, HA is regarded as the “queen” of skincare owing to its exceptional moisturizing properties. In the food industry, its dual benefits for health and beauty have gained popularity. This article employs a “Best All-rounder” award ceremony concept to showcase HA's unique properties and contributions while revealing the chemical basis behind its versatility, offering readers insights into this multifunctional biomolecule's role in modern life.

Key words: Hyaluronic acid, Glycosaminoglycan, Multifunctional biomolecule