大学化学 >> 2020, Vol. 35 >> Issue (2): 92-97.doi: 10.3866/PKU.DXHX201906020

师生笔谈 上一篇    下一篇

浅谈几种同分异构体的质谱解析

钱俊红,夏玮,张文清,刘海燕,胡坪,王燕*()   

  • 收稿日期:2019-06-11 录用日期:2019-07-04 发布日期:2019-08-19
  • 通讯作者: 王燕 E-mail:wangy@ecust.edu.cn
  • 基金资助:
    华东理工大学基础课程教学团队建设项目(YJ0126123);谱学导论上海市重点课程;华东理工大学专业核心课程项目

Discussion on Mass Spectrometric Analysis of Several Isomers

Junhong Qian,Wei Xia,Wenqing Zhang,Haiyan Liu,Ping Hu,Yan Wang*()   

  • Received:2019-06-11 Accepted:2019-07-04 Published:2019-08-19
  • Contact: Yan Wang E-mail:wangy@ecust.edu.cn
  • Supported by:
    华东理工大学基础课程教学团队建设项目(YJ0126123);谱学导论上海市重点课程;华东理工大学专业核心课程项目

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摘要：

质谱解析是波谱分析课程教学的重点和难点，有机化合物裂解规则是质谱解析的关键，掌握有机化合物质谱的碎裂规律对于化合物结构解析很有帮助。本文从本科教学的实际出发，对三类常见同分异构体羧酸-酯、醇-醚及直链-支链化合物的质谱碎裂规律进行梳理，并通过具体质谱解析实例帮助学生学习、掌握有机化合物的基本裂解规律，提高质谱解析能力。

关键词: 质谱解析, 同分异构体, 裂解规律, 羰基化合物, 饱和含氧化合物

Abstract:

Mass spectrometric analysis is a key and difficult issue in teaching of spectroscopic analysis course. Moreover, fragmentation patterns are the key points for mass spectrometric analysis. Understanding the dissociation rules of organic compounds will help the students to analyze the chemical structures. From the viewpoint of teaching practice, we review in this paper the fragmentation patterns of some common isomers such as acids-esters, alcoholsethers, and straight-chain and branched-chain alkyl groups. In addition, some classic examples were presented to help the students to grasp the fragmentation patterns as well as to improve their ability of mass spectrometric analysis.

Key words: Mass spectrometric analysis, Isomers, Fragmentation pattern, Carbonyl compounds, Saturated oxygenates.