大学化学 >> 2023, Vol. 38 >> Issue (11): 142-147.doi: 10.3866/PKU.DXHX202304034

所属专题： 化学科普(2024)

科普 上一篇    下一篇

治疗癌症的“奇兵”——微纳米马达

姜满乐1, 张荡1, 张箭2, 徐平1, 王磊1,*()   

  1. 1 哈尔滨工业大学化工与化学学院, 哈尔滨 150001
    2 哈尔滨医科大学基础医学院, 哈尔滨 150081
  • 收稿日期:2023-04-10 录用日期:2023-09-04 发布日期:2023-09-12
  • 通讯作者: 王磊 E-mail:leiwang_chem@hit.edu.cn
  • 基金资助:
    国家自然科学基金(52073071);黑龙江省自然科学基金优秀青年基金(YQ2022E021)

Micro/nanorobots: An "Ingenious Shocking Military" towards Cancer Treatment

Manle Jiang1, Dang Zhang1, Jian Zhang2, Ping Xu1, Lei Wang1,*()   

  1. 1 School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China
    2 School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China
  • Received:2023-04-10 Accepted:2023-09-04 Published:2023-09-12
  • Contact: Lei Wang E-mail:leiwang_chem@hit.edu.cn

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摘要：

目前癌症的发病率正在逐渐上升，为实现精准且低毒害的治疗目标，科学家们设计了智能的微纳米马达材料。这类微小的智能装置可在外界条件控制下靶向于甚至进入癌细胞，从而靶向运输药物，最终实现癌症的治疗。为了使这项技术得到更广泛的认识, 本文采用拟人化手法，以微纳米马达与免疫细胞共同消灭癌细胞的故事为主体，简单介绍微纳米马达的制备、驱动方式以及治疗原理。

关键词: 微纳米马达, 癌症治疗, 微纳米机器人, 靶向治疗, 免疫治疗

Abstract:

In recent decades, an escalating incidence of tumors has been observed, necessitating more precise and less side-effect-prone therapies. Micro/nanorobots have been successfully engineered to address this challenge. These minute intelligent machines are capable of navigating to, and even infiltrating, tumor cells or tissues under external control. This enables targeted drug delivery and precise tumor therapy. To elucidate this sophisticated technology to a general audience, this paper adopts a personification style. Utilizing an engaging "battle narrative between micro/nanorobots and tumor cells", we briefly outline the design, fabrication, propulsion mechanisms, and therapeutic principles for a wider readership.

Key words: Micro/nanomotors, Tumor treatment, Micro/nanorobots, Targeted treatment, Immunotherapy