大学化学 >> 2024, Vol. 39 >> Issue (9): 122-127.doi: 10.3866/PKU.DXHX202311022

所属专题： 化学科普(2024)

科普 上一篇    下一篇

青霉素家族专访直播录

李沛凌1, 冯清2, 袁红玲2, 王芹2   

  1. 1 华中科技大学同济医学院基础医学院, 武汉 430070;
    2 华中科技大学化学与化工学院, 武汉 430074
  • 收稿日期:2023-11-06 修回日期:2023-12-25 发布日期:2024-02-20
  • 通讯作者: 袁红玲, 王芹 E-mail:yhl_14@hust.edu.cn;qwang@hust.edu.cn
  • 基金资助:
    湖北省高等学校省级教学研究项目(2018050)；华中科技大学教学研究专项项目(2023019)

Live Interview Recording about the Penicillin Family

Peiling Li1, Qing Feng2, Hongling Yuan2, Qin Wang2   

  1. 1 School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China;
    2 School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
  • Received:2023-11-06 Revised:2023-12-25 Published:2024-02-20
  • Contact: Hongling Yuan, Qin Wang E-mail:yhl_14@hust.edu.cn;qwang@hust.edu.cn

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摘要： 青霉素是世界上发现的第一种抗菌药，目前已发展为含有β-内酰胺结构的抗菌药家族，在临床上广泛使用。本文以直播专访录的形式介绍了青霉素家族及主要成员。通过青霉素家族成员代表与主持人的对话，向人们生动展示了青霉素家族成员的抗菌机制、作用特点和临床应用，以此促进人们进一步树立合理应用抗生素的健康意识。

关键词: 青霉素, 半合成青霉素, β-内酰胺环, 抗生素

Abstract: Penicillin was the first antibacterial drug discovered in the world. Now it has been developed to be a family of antimicrobial drugs containing β-lactam, which is widely used in clinic. This article introduces the penicillin family and its main members in the form of a live interview recording. Through a dialogue between representatives of the penicillin family and the host, the antibacterial mechanism, characteristics, and clinical applications of the penicillin family members are vividly presented to the public. It aims to promote people’s awareness of the rational use of antibiotics.

Key words: Penicillin, Semi-synthetic penicillin, β-lactam ring, Antibiotics