大学化学 >> 2026, Vol. 41 >> Issue (1): 406-412.doi: 10.12461/PKU.DXHX202504022

所属专题： 化学实验数字化设计竞赛获奖作品

专题 上一篇    

交互式数字化有机合成教学实验——设计流程和案例展示

曹若宇, 陈嘉欣, 胡加恩, 翟优婷, 付佳聪, 侯立芬, 闫学斌, 李艳阳, 李恺, 臧双全   

  1. 郑州大学化学学院, 郑州 450001
  • 收稿日期:2025-04-08 录用日期:2025-07-23 发布日期:2025-12-30
  • 通讯作者: 李艳阳, 李恺 E-mail:yyli@zzu.edu.cn;likai@zzu.edu.cn Yanyang Li, Kai Li
  • 基金资助:
    郑州大学校级教育教学改革研究与实践项目(2024ZZUJGXM007, 2024ZZUJGXM051, 2025ZZUJGXM115)；河南省高等教育教学改革研究与实践项目(2024SJGLX0033)；高等教育研究项目(2025SXHLX083)

Interactive Digital Experiment for Organic Synthesis: Designing Process and Case Presentation

Ruoyu Cao, Jiaxin Chen, Jiaen Hu, Youting Zhai, Jiacong Fu, Lifen Hou, Xuebin Yan, Yanyang Li, Kai Li, Shuangquan Zang   

  1. College of Chemistry, Zhengzhou University, Zhengzhou 450001, China
  • Received:2025-04-08 Accepted:2025-07-23 Published:2025-12-30
  • Contact: Yanyang Li, Kai Li E-mail:yyli@zzu.edu.cn;likai@zzu.edu.cn

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摘要： 本论文中，我们设计了一种交互式数字化实验教学模式，利用数字化技术对目标产物进行逆合成分析，并对不同的合成路线对应的成本、安全性、产率等进行评估，筛选出适于实验教学的合成路线，完善每一条路线可能遇到的实验操作问题，设置多种可能的解决方案，最终以互动视频的形式呈现为数字化教学实验项目。在此模式下，教师能够利用数字化技术来设计实验路线、触发随机事件，引导学生发现问题、解决问题，最终完成整个实验过程。这种交互式实验教学模式有望改变传统线上实验的单线条教学叙事形式，形成具有高自由度、个性化、实时反馈、高区分度特点的新型数字化实验，并应用于更多的实验教学领域。

关键词: 交互式, 数字化, 有机合成, 互动视频

Abstract: In this work, we developed an interactive digital teaching model for experimental chemistry education. The approach employs digital technologies to perform retrosynthetic analysis of target compounds while evaluating different synthetic routes based on cost, safety, and yield parameters to identify optimal pathways for teaching purposes. Each route is systematically optimized to address potential operational challenges, with multiple troubleshooting solutions incorporated. The final output is presented as an interactive video-based digital experiment. Within this framework, instructors can utilize digital tools to design experimental pathways and generate randomized events, thereby guiding students through problem identification, solution development, and experimental completion. This interactive teaching paradigm represents a significant advancement over traditional linear virtual experiments, offering enhanced flexibility, personalization, real-time feedback, and improved differentiation capabilities. The methodology demonstrates considerable potential for broader application in experimental chemistry education.

Key words: Interactive, Digitization, Organic synthesis, Interactive video