大学化学 >> 2026, Vol. 41 >> Issue (10): 268-276.doi: 10.12461/PKU.DXHX202509134

化学实验 上一篇    

半胱氨酸修饰的金纳米溶胶的光学性质研究

尉云平1, 刘星岑1, 林猛1, 黄永清2   

  1. 1 山东大学化学与化工学院, 山东 济南 250100;
    2 山东科技大学化学与生物工程学院, 山东 青岛 266590
  • 收稿日期:2025-09-29 录用日期:2025-11-06 发布日期:2026-10-13
  • 通讯作者: 刘星岑 E-mail:liuxingcen@sdu.edu.cn Xingcen Liu
  • 基金资助:
    山东大学实验室建设与管理研究项目(sy20242201, sy20253202)；山东省本科高校教学改革研究项目(Z2023084)

Optical properties of cysteine-modified gold nanocolloids

Yunping Wei1, Xingcen Liu1, Meng Lin1, Yongqing Huang2   

  1. 1 School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, Shandong Province, China;
    2 College of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, Shandong Province, China
  • Received:2025-09-29 Accepted:2025-11-06 Published:2026-10-13
  • Contact: Xingcen Liu E-mail:liuxingcen@sdu.edu.cn

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摘要： 利用水热合成法和置换稳定剂方法制备半胱氨酸修饰的金纳米溶胶，采用紫外-可见分光光度法表征溶胶光学性质，用于考察浓度、pH、时间、金属离子对溶胶稳定性的影响。本实验综合了样品的制备、表征和性质研究，使用了紫外-可见分光光度计，内容涉及仪器分析、物理化学、无机化学等多学科知识和基本操作。通过该实验，学生可进一步了解溶胶的物理化学性质，提高学生综合实验能力，激发学生对金纳米溶胶在化学、医学等领域应用的学习兴趣。

关键词: 金纳米粒子, 溶胶稳定性, 半胱氨酸, 紫外-可见吸收光谱

Abstract: Cysteine-modified gold nanocolloids were synthesized via hydrothermal synthesis and ligand displacement methods. The optical characteristics of the nanocolloids were systematically investigated using UV-Vis spectrophotometry to evaluate the effects of concentration, pH, temporal stability, and metal ion interactions on colloidal stability. This integrated experiment encompasses nanocolloid preparation, characterization, and property analysis, incorporating multidisciplinary techniques from instrumental analysis, physical chemistry, and inorganic chemistry. The study not only enhances students’ understanding of colloidal physicochemical properties but also develops comprehensive experimental skills, while fostering research interest in the applications of gold nanocolloids across chemical and biomedical fields.

Key words: Gold nanoparticles, Colloid stability, Cysteine, Ultraviolet-visible spectrophotometry