大学化学

所属专题： 面向本科生教学的金属有机化学

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化学中的分子芭蕾：烯烃复分解如何重塑分子世界

叶富1, 袁伟明2   

  1. 1 贵州工程应用技术学院化学工程学院, 贵州 毕节 551700;
    2 华中科技大学化学与化工学院, 湖北 武汉 430074
  • 收稿日期:2026-01-05 录用日期:2026-02-09
  • 通讯作者: 袁伟明 E-mail:yuanwm@hust.edu.cn Weiming Yuan
  • 基金资助:
    国家自然科学基金(22571104)；国家重点研发计划(2024YFA1510500)；贵州省基础研究计划面上项目(QKHJC-MS[2026]221)

The molecular ballet in chemistry: how olefin metathesis reshapes the molecular world

Fu Ye1, Weiming Yuan2   

  1. 1 College of Chemical Engineering, Guizhou University of Engineering Science, Bijie 551700, Guizhou Province, China;
    2 School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, Wuhan 430074, Hubei Province, China
  • Received:2026-01-05 Accepted:2026-02-09
  • Contact: Weiming Yuan E-mail:yuanwm@hust.edu.cn

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摘要： 烯烃复分解反应作为一项革命性化学技术，通过金属卡宾催化剂介导的碳碳双键断裂与重组，可以实现分子的模块化精准合成。该反应已在药物研发、先进材料合成及绿色化学等领域展现出强大的应用价值，并于2005年获得诺贝尔化学奖。未来，随着新催化体系的开发及与人工智能、生物体系的融合，烯烃复分解反应将继续推动可持续制造与分子科学前沿发展，深刻影响人类创造新物质的方式。

关键词: 烯烃复分解, 金属卡宾, 催化化学, 分子科学

Abstract: Olefin metathesis, a revolutionary chemical technology, enables modular and precise molecular synthesis through metal-carbene-catalyzed cleavage and reorganization of carbon-carbon double bonds. This reaction has demonstrated significant applications in pharmaceutical research, advanced material synthesis, and green chemistry, earning the Nobel Prize in Chemistry in 2005. Future developments in catalytic systems, combined with advancements in artificial intelligence and biological integration, will further propel olefin metathesis in sustainable manufacturing and molecular science frontiers, profoundly transforming humanity’s approach to molecular design.

Key words: Olefin metathesis, Metal carbene, Catalytic chemistry, Molecular science