冠醚在人工离子转运系统中的应用

doi:10.12461/PKU.DXHX202501010

大学化学 >> 2026, Vol. 41 >> Issue (2): 232-237.doi: 10.12461/PKU.DXHX202501010

冠醚在人工离子转运系统中的应用

谭婧, 郑波, 高玲燕

西北大学化学与材料科学学院, 教育部合成与天然功能分子重点实验室, 西安 710127

收稿日期:2025-01-06 录用日期:2025-02-24 发布日期:2025-12-27
通讯作者: 郑波, 高玲燕 E-mail:zhengbo@nwu.edu.cn;gaolingyan@nwu.edu.cn Bo Zheng, Lingyan Gao
基金资助:
陕西省基础科学(化学、生物学)研究院青年项目(23JHQ016)

Application of Crown Ether-Based Artificial Ion Transporters

Jing Tan, Bo Zheng, Lingyan Gao

Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China

Received:2025-01-06 Accepted:2025-02-24 Published:2025-12-27
Contact: Bo Zheng, Lingyan Gao E-mail:zhengbo@nwu.edu.cn;gaolingyan@nwu.edu.cn

摘要/Abstract

摘要： 冠醚作为一类结构特殊的醚类化合物，已逐渐为人们所认识。近年来，冠醚在构建人工跨膜离子转运体系方面不断推陈出新，引起科学家们的普遍关注。利用不同的冠醚结构和组装基元在构筑跨膜人工离子通道、海水处理、盐湖提锂及电池领域等方面的探索，极大地扩展了冠醚类化合物的研究范畴；结合超分子化学和生物学的原理，以及不同学科的交叉融合，这些新颖结构和独特功能的新型仿生人工离子转运体将在医药和化学化工产业中发挥重要的作用。

关键词: 冠醚, 跨膜运输, 选择分离, 碱金属

Abstract: Crown ethers, a distinctive class of ether compounds characterized by their unique structural features, have garnered increasing recognition in the scientific community. Recent advancements have witnessed remarkable innovations in the application of crown ethers for constructing artificial transmembrane ion transport systems. The utilization of diverse crown ether structures and assembly motifs has significantly broadened the research landscape, encompassing the development of transmembrane artificial ion channels, seawater treatment, lithium extraction from salt lakes, and battery technologies. By integrating principles from supramolecular chemistry and biology, along with interdisciplinary approaches, these novel biomimetic artificial ion transporters, distinguished by their innovative structures and unique functionalities, are poised to make substantial contributions to the pharmaceutical and chemical industries.

Key words: Crown ether, Transmembrane transport, Selective separation, Alkali Metals

谭婧, 郑波, 高玲燕. 冠醚在人工离子转运系统中的应用[J]. 大学化学, 2026, 41(2): 232-237.

Jing Tan, Bo Zheng, Lingyan Gao. Application of Crown Ether-Based Artificial Ion Transporters[J]. University Chemistry, 2026, 41(2): 232-237.

链接本文: https://www.dxhx.pku.edu.cn/CN/10.12461/PKU.DXHX202501010

https://www.dxhx.pku.edu.cn/CN/Y2026/V41/I2/232

参考文献

[1] (a) Pedersen, C. J. J. Am. Chem. Soc. 1967, 89 (10), 2495. (b) Pedersen, C. J. J. Am. Chem. Soc. 1967, 89 (26), 7017.
[2] (a) Cram, D. J.; Cram, J. M. Science 1974, 183 (4127), 803. (b) Lehn, J. M. Pure&Appl. Chem. 1978, 50, 871.
[3] The 1987 Nobel Prize in Chemistry. [2024-12-27]. https://www.nobelprize.org/prizes/chemistry/1987/press-release/
[4] Williams, G. T.; Haynes, C. J. E.; Fares, M.; Caltagirone, C.; Hiscock, J. R.; Gale, P. A. Chem. Soc. Rev. 2021, 50, 2737.
[5] Huang, T.; Alyami, M.; Kashab, N. M.; Nunes, S. P. J. Mater. Chem. A 2021, 9, 18102.
[6] 阮文娟, 李悦, 耿文超, 郭东升. 大学化学, 2023, 38 (12), 114.
[7] Gokel, G. W.; Leevy, W. M.; Weber, M. E. Chem. Rev. 2004, 104, 2723.
[8] 邢其毅, 裴伟伟, 徐瑞秋, 裴坚. 基础有机化学. 第4版. 北京: 北京大学出版社, 2017: 319–330.
[9] Djalali, S.; Marqués, P. S.; Frank, B. D.; Zeininger, L. Adv. Funct. Mater. 2022, 32 (2), 2107688.
[10] Ranno, L.; Tan, Y. Z.; Ong, C. S.; Guo, X.; Koo, K. N.; Li, X.; Wang, W.; Serna, S.; Liu, C.; Rusli; et al. Nat. Commun. 2024, 15, 3820.
[11] He, L.; Zhang, T.; Zhu, C.; Yan, T.; Liu, J. Chem. Eur. J. 2023, 29 (25), e202300044.
[12] Johnson, T. G.; Langton, M. J. J. Am. Chem. Soc. 2023, 145, 27167.
[13] Shen, J.; Ren, C.; Zeng, H. Acc. Chem. Res. 2022, 55, 1148.
[14] Ren, C.; Shen, J.; Zeng, H. J. Am. Chem. Soc. 2017, 139, 12338.
[15] Shen, J.; Ye, R.; Zeng, H. Angew. Chem. Int. Ed. 2021, 60, 12924.
[16] Huo, Y.; Zeng, H. Acc. Chem. Res. 2016, 49, 922.
[17] Zhang, H.; Ye, R.; Mu, Y.; Li, T.; Zeng, H. Nano Lett. 2021, 21, 1384.
[18] Ren, C.; Chen, F.; Ye, R.; Ong, Y. S.; Lu, H.; Lee, S. S.; Ying, J. Y.; Zeng, H. Angew. Chem. Int. Ed. 2019, 58, 8034.
[19] Shen, J.; Han, J. J. Y.; Ye, R.; Zeng, H. Sci China Chem. 2021, 64 (12), 2154.
[20] Ye, R.; Ren, C.; Shen, J.; Li, N.; Chen, F.; Roy, A.; Zeng, H. J. Am. Chem. Soc. 2019, 141, 9788.
[21] Chen, S.; Wang, Y.; Nie, T.; Bao, C.; Wang, C.; Xu, T.; Lin, Q.; Qu, D. H.; Gong, X.; Yang, Y; et al. J. Am. Chem. Soc. 2018, 140, 17992.
[22] Wang, C.; Yang, H.; Xiang, Y.; Pang, S.; Bao, C.; Zhu, L. Front. Chem. 2021, 9, 667472.
[23] Wang, C.; Wang, S.; Yang, H.; Xiang, Y.; Wang, X.; Bao, C.; Zhu, L.; Tian, H.; Qu, D. H. Angew. Chem. Int. Ed. 2021, 60, 14836.
[24] Ye, K.; Zhang, Z.; Yan, Z.; Pang, S.; Yang, H.; Sun, X.; Liu, C.; Zhu, L.; Lian, C.; Bao, C. Sci. China Chem. 2023, 66 (8), 2300.
[25] Li, N.; Shen, J.; Ang, G. K.; Ye, R.; Zeng, H. CCS Chem. 2020, 2, 2269.
[26] Li, N.; Chen, F.; Shen, J.; Zhang, H.; Wang, T.; Ye, R.; Li, T.; Loh, T. P.; Yang, Y. Y.; Zeng, H. J. Am. Chem. Soc. 2020, 142, 21082.
[27] Wang, W. Z.; Huang, L. B.; Zheng, S. P.; Moulin, E.; Gavat, O.; Barboiu, M.; Giuseppone, N. J. Am. Chem. Soc. 2021, 143, 15653.
[28] Li, C.; Wu, Y.; Zhu, Y.; Yan, J.; Liu, S.; Xu, J.; Fa, S.; Yan, T.; Zhu, D.; Yan, Y.; et al. Adv. Mater. 2024, 36, 2312352.
[29] Yang, H.; Yi, J.; Pang, S.; Ye, K.; Ye, Z.; Duan, Q.; Yan, Z.; Lian, C.; Yang, Y.; Zhu, L.; et al. Angew. Chem. Int. Ed. 2022, 61, e202204605.
[30] Ye, T.; Hou, G.; Li, W.; Wang, C.; Yi, K.; Liu, N.; Liu, J.; Huang, S.; Gao, J. Nat. Commun. 2021, 12, 5231.
[31] Ye, T.; Gao, H.; Li, Q.; Liu, N.; Liu, X.; Jiang, L.; Gao, J. Angew. Chem. Int. Ed. 2024, 63, e202316161.
[32] Jiang, C.; Bai, S.; Li, J.; Wang, M.; Zhou, Y.; Hou, Y. J. Membr. Sci. 2025, 714, 123372.
[33] Li, J.; Shi, Y.; Qi, C.; Zhang, B.; Xing, X.; Li, Y.; Chen, T.; Mao, X.; Zuo, Z.; Zhao, X.; et al. Angew. Chem. Int. Ed. 2023, 62, e202309918.
[34] Chen, Q.; Lin, M.; Li, X.; Du, Z.; Liu, Y.; Tang, Y.; Yan, Y.; Zhu, K. Angew. Chem. Int. Ed. 2024, e202407575.
[35] Li, M.; Wu, J.; You, Z.; Dai, Z.; Gu, Y.; Shi, L.; Wu, M.; Wen, Z. Angew. Chem. Int. Ed. 2024, 63, e202403521.
[36] Sauvage, J. P. Angew. Chem. Int. Ed. 2017, 56, 11080.
[37] Stoddart, J. F. Angew. Chem. Int. Ed. 2017, 56, 11094.
[38] Feringa, B. L. Angew. Chem. Int. Ed. 2017, 56, 11060.
[39] Balzani, V.; Credi, A.; Raymo, F. M.; Stoddart, J. F. Angew. Chem. Int. Ed. 2000, 39, 3348.
[40] Zheng, B.; Wang, F.; Donga, S.; Huang, F. Chem. Soc. Rev. 2012, 41, 1621.
[41] Cakmak, S. E.; Leigh, D. A.; McTernan, C. T.; Nussbaumer, A. L. Chem. Rev. 2015, 115, 10081.
[42] 成楚旸. 大学化学, 2017, 32 (1), 1.

冠醚在人工离子转运系统中的应用

Application of Crown Ether-Based Artificial Ion Transporters

PDF

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 7

Metrics

推荐阅读 0

[1]	陈万平. 知识逻辑的构建及推理下的发现：活泼金属与氧气反应的规律总结[J]. 大学化学, 2026, 41(2): 95 -102 .
[2]	袁文玉, 王颖, 李淑妮, 朱晓林, 翟全国, 高胜利. 碱金属的制备与纯化[J]. 大学化学, 2026, 41(2): 218 -231 .
[3]	王颖, 翟全国, 王志强, 雷青娟, 高胜利. 无机化学中“碱金属元素”教学内容的重构[J]. 大学化学, 2025, 40(6): 85 -92 .
[4]	梁作中, 魏灵灵, 曹译文, 魏韵涵, 史海媚, 郑浩铨, 高胜利. 基础课教学中培养本科生科研素养的探索——以《无机化学》碱金属/碱土金属配合物为例[J]. 大学化学, 2024, 39(7): 247 -263 .
[5]	王志鹏, 邱天, 沙耀武. 学生园地关于多维穴醚类似结构的构想[J]. 大学化学, 2013, 28(6): 75 -79 .
[6]	刘旭青, 张树永. 碱金属单质还原能力与还原活性顺序差异的讨论[J]. 大学化学, 2013, 28(3): 55 -60 .
[7]	金冲, 洪玠巍, 张传杰, 熊世豪. 碱金属与碱土金属密堆积结构的研究[J]. 大学化学, 2013, 28(2): 65 -70 .