大学化学 >> 2022, Vol. 37 >> Issue (3): 2105010.doi: 10.3866/PKU.DXHX202105010

师生笔谈 上一篇    下一篇

利用核磁共振氢谱分析异构化产物

袁耀锋(), 王宝绪, 黄良森, 成佳佳   

  • 收稿日期:2021-05-28 录用日期:2021-06-02 发布日期:2021-06-07
  • 通讯作者: 袁耀锋 E-mail:yaofeng_yuan@fzu.edu.cn
  • 作者简介:袁耀锋, Email: yaofeng_yuan@fzu.edu.cn
  • 基金资助:
    福建省本科高校教育教学改革研究项目;福州大学一流本科教学改革建设项目;中国高等教育理科教育专业委员会高等理科教育研究课题

Analysis of Isomerization Products by Proton Nuclear Magnetic Resonance Spectroscopy

Yaofeng Yuan(), Baoxu Wang, Liangsen Huang, Jiajia Cheng   

  • Received:2021-05-28 Accepted:2021-06-02 Published:2021-06-07
  • Contact: Yaofeng Yuan E-mail:yaofeng_yuan@fzu.edu.cn

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摘要：

核磁共振是解析有机化合物结构的一种常用的方法，也是有机波谱分析课程教学中的重点内容之一。本文结合三个实例介绍了核磁共振氢谱解析思路，理论与科研实际相结合，利用核磁共振氢谱判断产物中异构体的结构，通过峰组的积分面积确定异构体的比例，以便培养学生的科学素养，激发学生的学习兴趣，提高谱图的解析能力。

关键词: 核磁共振氢谱, 异构体, 化学位移, 耦合常数, 结构解析

Abstract:

Nuclear Magnetic Resonance (NMR) is a common method to analyze the structure of organic compounds, and it is also one of the important contents in the course of organic spectrum analysis. This paper introduces the idea of 1H NMR analysis, combining theory with three examples of scientific research practice, using 1H NMR to identify the structure of isomers in organic synthetic products, and determine the proportion of isomers by the integral area of peak group, in order to cultivate students' scientific literacy, stimulate students' interest in learning and improving the ability of spectrum analysis.

Key words: 1H NMR spectroscopy, Isomers, Chemical shifts, Coupling constants, Structural analysis