大学化学 >> 2023, Vol. 38 >> Issue (12): 51-60.doi: 10.3866/PKU.DXHX202306007

所属专题： 大学化学基础与创新药物研发前沿

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高阶能力导向进阶式研究性学习模式探索与实践——以“药物化学”课程为例

郭文婷1,*(), 赵丽1,*(), 汪宝堆2, 马妍1, 赵仲丽1   

  1. 1 兰州交通大学化学化工学院, 兰州 730070
    2 兰州大学化学化工学院, 兰州 730000
  • 收稿日期:2023-06-02 录用日期:2023-06-26 发布日期:2023-12-19
  • 通讯作者: 郭文婷,赵丽 E-mail:guowenting@mail.lzjtu.cn;zhaol@mail.lzjtu.cn
  • 基金资助:
    兰州交通大学2022年重点教改项目(JGZ202205);兰州交通大学2022年重点教改项目(JGZ202203);2023年兰州交通大学校级课程思政示范课程(1010070957);2022年兰州交通大学《药物化学》校级一流课程(101025060134);兰州大学教育教学改革研究项目(202120);2023甘肃省高等教育教学成果培育项目;2022甘肃省高等教育教学成果培育项目

Exploration and Practice of Higher-Order Competency-Oriented Progressive Research Learning Model: A Case Study of a "Pharmaceutical Chemistry" Course

Wenting Guo1,*(), Li Zhao1,*(), Baodui Wang2, Yan Ma1, Zhongli Zhao1   

  1. 1 School of Chemistry and Chemical Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China
    2 School of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China
  • Received:2023-06-02 Accepted:2023-06-26 Published:2023-12-19
  • Contact: Wenting Guo, Li Zhao E-mail:guowenting@mail.lzjtu.cn;zhaol@mail.lzjtu.cn

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摘要：

针对药物化学课程教学存在的问题，提出高阶能力导向进阶式研究性学习模式的教学创新。采用P-MASE研究性学习模型与进阶式教学活动设计相结合，创建以高阶能力为导向的“案例趣研+创研活动+项目挑战”进阶式教学活动，搭建教学场景，融入教学内容。学生在教师指导下通过P-MASE (即引入问题Problem-寻找方法Method-科学分析Analysis-有效解决Solution-效果评价Evaluation五个环节)推进药物化学研究性学习，完成理论构建，同时促进提升学生科研能力和创新思维。通过分析药物化学课程达成度证实，该模式能够有效提高课程高阶性、创新性和挑战度。

关键词: 药物化学, 高阶能力导向, 研究性学习模型, 进阶式教学活动

Abstract:

In response to the issues in the teaching of the medicinal chemistry course, we propose an innovative teaching approach based on a higher-order skills-oriented advanced research-oriented learning model. By combining the P-MASE research-oriented learning model with advanced instructional activity design, we create a higher-order skills-oriented teaching activity that integrates "interesting case research + creative research activities + project challenges", and construct a teaching scenario that incorporates the instructional content. Under the guidance of teachers, students advance their research-oriented learning in medicinal chemistry through the P-MASE framework, which involves problem identification, method exploration, scientific analysis, effective solution, and evaluation of outcomes. This approach facilitates theoretical development and enhances students' research and innovation thinking skills. Through an analysis of the achievement of the medicinal chemistry course, it is confirmed that this model can effectively enhance the higher-order nature, innovation, and challenge of the course.

Key words: Medicinal chemistry, Higher-order competence orientation, Research-oriented learning model, Activities of progressive teaching