大学化学 >> 2023, Vol. 38 >> Issue (12): 45-50.doi: 10.3866/PKU.DXHX202306064

所属专题： 大学化学基础与创新药物研发前沿

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浅谈创新药物研究案例在有机化学教学中的应用

闵真立(), 王婷, 陈亚军, 杨曦亮   

  • 收稿日期:2023-06-27 录用日期:2023-08-07 发布日期:2023-08-14
  • 通讯作者: 闵真立 E-mail:minzhenli@wust.edu.cn
  • 基金资助:
    武汉科技大学研究生教育教学改革研究项目(Yjg202213)

A Brief Elaboration on the Application of Innovative Drug Research Cases in Organic Chemistry Teaching

Zhenli Min(), Ting Wang, Yajun Chen, Xiliang Yang   

  • Received:2023-06-27 Accepted:2023-08-07 Published:2023-08-14
  • Contact: Zhenli Min E-mail:minzhenli@wust.edu.cn

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摘要：

有机化学是药学专业的重要基础课，与药物化学和创新药物研究联系紧密。有机化学内容庞杂，其中价键理论等与创新药物设计相关的内容抽象、难懂。将创新药物研究的案例引入有机化学课堂教学，或者结合相关软件，展示有机小分子与生物大分子的相互作用，能使得这些知识点的教学更加形象生动，易于接受，同时，能加深学生对有机化学与药学关系的了解，激发学生的学习兴趣和主动性，提高教学质量。

关键词: 有机化学, 药学, 创新药物研究, 教学案例

Abstract:

Organic chemistry serves as a fundamental course in pharmaceutical studies, which is closely associated with medicinal chemistry and innovative drug research. With its multifarious and complex content, certain topics in organic chemistry, such as the theory of chemical bonding relevant to innovative drug design, can be abstract and challenging to comprehend. Integrating case studies from innovative drug research into organic chemistry classroom teaching, along with the use of relevant software to demonstrate the interactions between organic small molecules and biomacromolecules, can make these concepts more vivid, accessible, and engaging for students. Moreover, this approach deepens students' understanding of the relationship between organic chemistry and pharmacy, and ignites their interest and proactivity in learning, which ultimately enhances the overall teaching quality.

Key words: Organic chemistry, Pharmacy, Innovative drug research, Teaching cases