大学化学 >> 2025, Vol. 40 >> Issue (2): 11-19.doi: 10.12461/PKU.DXHX202402048

所属专题: 教学型仪器的研制&改进与实验教学

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纳米孔道单分子电化学测量仪的实验教学应用与课程设计探索

胡正利1, 应佚伦1, 王佳1, 钟诚兵1, 孔璇凤2, 余晓冬2, 章文伟2, 张剑荣2, 龙亿涛1   

  1. 1 南京大学化学化工学院, 分子传感与成像中心, 南京 210023;
    2 南京大学化学化工学院, 化学国家级实验教学示范中心, 南京 210023
  • 收稿日期:2024-02-23 录用日期:2024-06-11 发布日期:2025-02-22
  • 通讯作者: 应佚伦 E-mail:yilunying@nju.edu.cn
  • 基金资助:
    南京大学2023年度教师数字化教学研究与实践项目;国家自然科学基金(22027806,22334006,22106066);教育部化学“101计划”——化学测量学实验课程建设项目;教育部第三批虚拟教研室建设试点——“101计划”化学测量学实验课程虚拟教研室

Experimental Course Design and Application of Nanopore Electrochemical Instrument for Single-Molecule Measurements

Zhengli Hu1, Yilun Ying1, Jia Wang1, Chengbing Zhong1, Xuanfeng Kong2, Xiaodong Yu2, Wenwei Zhang2, Jianrong Zhang2, Yitao Long1   

  1. 1 Molecular Sensing and Imaging Center (MSIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China;
    2 National Demonstration Center for Experimental Chemistry Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
  • Received:2024-02-23 Accepted:2024-06-11 Published:2025-02-22
  • Contact: Yilun Ying E-mail:yilunying@nju.edu.cn

摘要: “科研融合型”仪器分析与化学测量实验是南京大学化学类专业本科生“早期介入科研”的重要途径,以此类实验课程为载体融合思政教育,有利于帮助学生树立正确的价值观,对于全面培养学生的科研兴趣、科学品德和学术素养具有重要意义。本文以基于自制仪器开设的“纳米孔道电化学单分子测量”实验为例,探讨了“验证学习”到“自主探索”的两段式实验教学模式,提出课程思政整体设计框架,提炼严谨求实、自强创新、科技报国等思政元素有效融入实验教学全过程,引导鼓励学生主动学习科学前沿技术和科研成果,自觉将课堂知识延伸至课外自主探索科研活动,实现了价值-知识-能力“三位一体”育人目标,为“科研融合型”化学实验课程建设与教学改革提供借鉴。

关键词: 纳米孔道电化学, 单分子测量, 仪器分析实验, 课程思政, 科研融合

Abstract: Integrating scientific research with the experiments for analytical measurements is crucial for early engagement of chemistry undergraduates in Nanjing University. This approach not only facilitates practical scientific exploration but also integrates ideological and political education to help students correct values, nurture their research interests, and enhance their academic literacy. This paper presents a case study of the undergraduate course “Nanopore Electrochemical Measurement of Single Molecules”, conducted using a homemade instrument. The course adopts a student-centered two-phase experimental teaching mode that transitions from “verification learning” to “independent exploration”. Throughout the teaching process, the ideological and political elements such as self-improvement and innovation are integrated to inspire students to master cutting-edge scientific technologies and engage in independent exploratory activities. This course design effectively meets the educational goals of values, knowledge, and skills, providing valuable insights for developing and reforming chemistry experimental courses that incorporate scientific research.

Key words: Nanopore electrochemistry, Single-molecule measurement, Instrumental chemistry experiment, Ideological and political education, Scientific research integration