大学化学 >> 2026, Vol. 41 >> Issue (10): 203-215.doi: 10.12461/PKU.DXHX202510031

科普 上一篇    

长霉的食物可以吃吗?

李厚金1, 聂慧敏1, 周晓瑜1, 刘浩2, 蓝文健2   

  1. 1 中山大学化学学院, 广东 广州 510006;
    2 中山大学药学院, 广东 广州 510006
  • 收稿日期:2025-10-13 录用日期:2025-11-25 发布日期:2026-10-13
  • 通讯作者: 李厚金 E-mail:ceslhj@mail.sysu.edu.cn Houjin Li
  • 基金资助:
    广东省“基层科普行动计划”项目(GDKP2025-2-017);中山大学本科教学质量工程项目

Can Moldy Food Be Consumed?

Houjin Li1, Huimin Nie1, Xiaoyu Zhou1, Hao Liu2, Wenjian Lan2   

  1. 1 School of Chemistry, Sun Yat-Sen University, Guangzhou 510006, Guangdong Province, China;
    2 School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, Guangdong Province, China
  • Received:2025-10-13 Accepted:2025-11-25 Published:2026-10-13
  • Contact: Houjin Li E-mail:ceslhj@mail.sysu.edu.cn

摘要: 真(霉)菌在自然界中分布广泛。食物中富含的碳水化合物、水分、矿物质、维生素等营养成分,为微生物生长提供了适宜条件,几乎所有食品都存在被霉菌污染的风险。一旦食物(如谷物、坚果、面包等)出现肉眼可见的霉斑,其安全性便已受到严重威胁。真菌在生长繁殖过程中会产生真菌毒素,它严重危害食品质量与安全,可能导致神经系统与内分泌紊乱、肝肾损伤、繁殖障碍、免疫抑制、致癌与致畸等健康问题。然而在日常生活中,许多民众对霉变食物存在错误认知和不当做法,给健康带来隐患。本文介绍了常见食物霉变产生的真菌毒素的化学结构、毒性机制、毒素限量国家安全标准、检测手段、毒素污染控制规范与脱毒方法,以及受控发酵食品与自然长霉食品的核心区别,并提供了科学饮食建议,旨在提升公众对食品安全的重视,纠正对霉变食物的错误认识,并推动健康生活方式的养成。

关键词: 食品安全, 真菌毒素, 毒性机制, 科普

Abstract: Fungi (molds) are ubiquitously distributed in nature. The nutritional components in foodstuffs, including carbohydrates, moisture, minerals, and vitamins, create favorable conditions for microbial proliferation. Virtually all food products are susceptible to fungal contamination. When visible mold colonies appear on food items (e.g., cereals, nuts, bread), their safety becomes severely compromised. During growth and reproduction, fungi produce mycotoxins that significantly jeopardize food quality and safety, potentially causing various health disorders such as neurological and endocrine dysfunction, hepatorenal damage, reproductive abnormalities, immunosuppression, as well as carcinogenic and teratogenic effects. Nevertheless, prevailing public misconceptions and improper handling practices regarding mold-contaminated foods persist in daily life, posing substantial health risks. This article systematically examines the chemical structures and toxicological mechanisms of common mycotoxins derived from spoiled foods, along with national safety standards for permissible limits, analytical methodologies, contamination control protocols, and detoxification approaches. Furthermore, it elucidates the fundamental distinctions between controlled fermentation products and naturally mold-contaminated foods, while providing evidence-based dietary recommendations to enhance public awareness of food safety, rectify erroneous perceptions about moldy foods, and foster healthier lifestyle practices.

Key words: Food safety, Mycotoxins, Toxicological mechanisms, Public science education