大学化学 >> 2023, Vol. 38 >> Issue (8): 95-100.doi: 10.3866/PKU.DXHX202208102

化学实验 上一篇    下一篇

半硫杂竹脲[6]大环分子的合成与离子跨膜转运性质测定——推荐一个大学综合化学实验

鲁轶楠, 罗逸尘, 李艳, 孙鸿程(), 刘俊秋   

  • 收稿日期:2022-08-19 录用日期:2022-09-19 发布日期:2022-10-10
  • 通讯作者: 孙鸿程 E-mail:sunhc@hznu.edu.cn
  • 基金资助:
    2021年杭州师范大学教学建设与改革项目;2021年杭州师范大学“星光计划”项目

Synthesis of Macrocyclic Semithiobambus[6]uril for Transmembrane Anion Transportation: A Comprehensive Chemical Experiment for Undergraduate Students

Yinan Lu, Yichen Luo, Yan Li, Hongcheng Sun(), Junqiu Liu   

  • Received:2022-08-19 Accepted:2022-09-19 Published:2022-10-10
  • Contact: Hongcheng Sun E-mail:sunhc@hznu.edu.cn

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摘要：

介绍了一个以半硫杂竹脲[6]大环分子(stBU[6])为研究对象的综合实验，涉及制备、表征、性能测试等实验基础步骤。该实验与学科热点、学术前沿紧密结合，科教融合，通过一系列荧光测试，引导学生了解离子跨膜传输的作用机制，熟悉大型仪器使用，为学生拓展视野、提高综合实践能力等打好基础。

关键词: 荧光检测, 跨膜转运, 人工离子通道

Abstract:

Herein, a comprehensive experiment was carried out to study the macrocyclic molecules of semithiobambus[6]uril (stBU[6]), involving the preparation, characterization, and performance testing. Through a series of fluorescence tests, the students are guided to understand the mechanism of ion transmembrane transport, familiarize themselves with large-scale instruments, and broaden their horizons to lay a good foundation for improving their comprehensive practical skills.

Key words: Fluorescence detection, Transmembrane transport, Artificial ion channel