关键词: 光化学, 仲胺, 一锅法串联反应, 自由基反应

Abstract: This experiment integrates cutting-edge research from the field of organic photochemistry into undergraduate laboratory instruction. Utilizing benzaldehyde, aniline, and 4-isopropyl-1,4-dihydropyridines as starting materials, a visible-light-mediated one-pot multicomponent reaction was conducted under mild conditions to yield secondary amines efficiently. The experiment features cost-effective and readily available reagents, simple operation, and mild reaction conditions, alongside incorporating principles of green chemistry and organic synthesis methodology. Suitable for undergraduate laboratory teaching, it provides students with practical skills while deepening their comprehension of topics such as photochemical reactions, one-pot tandem reactions, and free radical processes. This experiment bridges the gap between cutting-edge research and talent cultivation, enhancing students’ abilities in scientific research, innovation, and practical application.

Key words: Photochemistry, Secondary amines, One-pot tandem reaction, Free radical reaction