大学化学 >> 2022, Vol. 37 >> Issue (12): 2209051.doi: 10.3866/PKU.DXHX202209051

所属专题： 第54届国际化学奥林匹克专刊

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神奇的手性螺环催化剂——第54届国际化学奥林匹克试题第8题解析

汤平平()   

  • 收稿日期:2022-09-20 录用日期:2022-10-08 发布日期:2022-10-25
  • 通讯作者: 汤平平 E-mail:ptang@nankai.edu.cn
  • 作者简介:汤平平，Email: ptang@nankai.edu.cn

Amazing Chiral Spiro Catalyst: Analysis of Problem 8 of the 54th International Chemistry Olympiad

Pingping Tang()   

  • Received:2022-09-20 Accepted:2022-10-08 Published:2022-10-25
  • Contact: Pingping Tang E-mail:ptang@nankai.edu.cn

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摘要：

手性化合物对人们的生命健康至关重要。第54届国际化学奥林匹克试题第8题以南开大学周其林院士团队发展的手性螺环催化剂为主要内容，考查了手性螺环配体SpiroPAP的合成路线，手性螺环催化剂Ir-SpiroPAP的制备，以及手性螺环催化剂在天然产物合成中的应用。

关键词: 手性, 螺环催化剂, 有机合成, 铱, 配合物

Abstract:

Chiral compounds are very important in people's life and health. Taking the chiral spiro catalyst developed by the team of academician Zhou Qilin of Nankai University as the main content of the 54th International Chemistry Olympiad, problem 8 investigated the synthesis route of chiral spiro ligand SpiroPAP, the preparation of chiral spiro catalyst Ir-SpiroPAP, and the application of chiral spiro catalyst in the synthesis of natural products.

Key words: Chirality, Spiro catalysts, Organic synthesis, Iridium, Complex