大学化学 >> 2022, Vol. 37 >> Issue (9): 2207072.doi: 10.3866/PKU.DXHX202207072

所属专题： 化学科普(2022)

科普 上一篇    下一篇

嘌呤家族的访谈报告

丁鹏中1, 朱荣秀2,*()   

  1. 1 山东大学基础医学院, 济南 250102
    2 山东大学化学与化工学院, 济南 250100
  • 收稿日期:2022-07-18 录用日期:2022-08-26 发布日期:2022-09-16
  • 通讯作者: 朱荣秀 E-mail:rxzhu@sdu.edu.cn
  • 作者简介:朱荣秀, Email: rxzhu@sdu.edu.cn
  • 基金资助:
    中国高等教育学会2021“理科教育研究”专项课题(21LKD02);山东大学教学改革项目(2022Y076)

Interview Report of Purine Family

Pengzhong Ding1, Rongxiu Zhu2,*()   

  1. 1 College of Basic Medical Sciences, Shandong University, Jinan 250102, China
    2 School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
  • Received:2022-07-18 Accepted:2022-08-26 Published:2022-09-16
  • Contact: Rongxiu Zhu E-mail:rxzhu@sdu.edu.cn

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摘要：

嘌呤对人体健康及生命活动具有十分重要的作用，然而嘌呤代谢异常会引起痛风。本文采用访谈报告的形式，介绍了嘌呤、腺嘌呤、鸟嘌呤、次黄嘌呤和黄嘌呤的结构、分布以及生理功能，并用简单易懂的方式向读者展示了嘌呤代谢生成尿酸的过程，痛风的诱因、发病机制以及预防和治疗措施。

关键词: 嘌呤, 痛风, 尿酸

Abstract:

Purines play an essential role in maintaining the normal life activities, but abnormal metabolism of purine can cause gout. In this paper, the structure, distribution and physiological functions of purine, adenine, guanine, hypoxanthine and xanthine are introduced in the form of an interview with the purines. Moreover, the process of purine metabolism to produce uric acid, and the etiology, pathogenesis, prevention and treatment measures of gout are also presented in a simple and easy-to-understand way.

Key words: Purine, Gout, Uric acid